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Analeptic-
CNS stimulent used to reverse drug-induced CNS depression, particularly Respiratory depression
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Examples of analeptics:
- Doxapram
- Strychnine
- Methylxanthines
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What is preferred over Analeptics?
Antagonists
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In excess, CNS stimulents can induce...
Convulsions
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Exceptions to Analeptics:
- Opioid antagonists
- a2 adrenergic antagonists
- benzodiazapine antagonists
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*What is the most commonly used analeptic?
Doxapram
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Doxapram=>
Stimulate Respiration
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Doxapram is labeled for use in:
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Under what circumstances is doxampram used?
- General Anasthesia
- Newborns
- Cardiopulmonary arrest
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In excess, Doxapram =>
- Hyperventilation
- Hypertertension
- Seizures
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Duration of action of Doxapram:
5-10 mins
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Today, strychnine is used only for...
PESTicide
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What receptors does Strychnine act on?
Glycine Antagonist
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Strychnine =>
Potent convulsant agent
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Examples of Methylxanthines:
- Caffeine
- Theophylline (tea)
- Theobromine
- Aminophyllines
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Weak bronchiodilators are used to Tx
- Asthma (bronchodilator in dogs, cats & horses)
- Cong Heart Dz (dilates coronary aa)
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*Weak bronchodilators include:
- Theophylline
- Aminophylline
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Which seizure medication is not used in cats?
Br
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What medication can cause acute hepatic necrosis in cats?
Diazapam
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Steady State of Phenobarb is mantained w/in...
14-16 days
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