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Cephalosporins
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This antibiotic is brokendown into 4 generations.
Cephalosporins
Are cephalosporins bactericidal or bacteriostatic?
Bactericidal
As the generations progress in cephalosporins, which type of bacteria do they become increasingly more capable of killing?
Gram negative
List the 6 antibiotics in the 1st generation of cepaholsporins.
cefadroxil
cefazolin
cephalexin
cephalothin
cephradine
cephapirin
What are cephalosporins in Generation 1 typically used for?
(3)
Surgical prophylaxis
URIs
Otitis media
True or False
Cephalosporins are considered Broad
spectrum antibiotics.
True
False
True
Name the 9 antibiotics that are in the 2nd Generation of cephalosporins.
cefotetan
cefoxitin
cefonicid
cefaclor
cefamandole
cefmetazole
cefuroxime
cefprozil
loracarbef
What is the Trade name for cefoxitin?
Mefoxin
How is Mefoxin administered?
IV and IM
What is Mefoxin used to treat?
(2)
Prophylaxis for ab and colorectal surgeries
Kills anaerobes
What are 2 Trade names for cefuroxime?
Kefurox
Ceftin
How is cefuroxime administered?
PO
What is cefuroxime used to treat?
(2)
Surgical prophylaxis
Does NOT kill anaerobes
Which Generation is the most potent against Gram-negative bacteria?
3rd Generation
Name the 8 antibiotics in Generation 3 of cephalosporins.
cefixime
cefotaxime
ceftazidime
cefpodoxime
ceftizoxime
ceftibuten
ceforperazone
ceftriaxone
What is the Trade name of cefixime?
Suprax
Which 3rd Generation antibiotic is best available oral cephalosporin agains gram-negative bacteria?
cefixime
What is a Trade name for ceftriaxone?
Rocephin
How is Rocephin administered?
IV and IM
How often can Rocephin be administered and why?
Once a day because it has a long half-life
What is Rocephin used to treat and why?
CNS infections because it easily passes the meninges and diffuses into CSF
What are 4 Trade names for ceftazidime?
Ceptaz
Fortaz
Tazidime
Tazicef
How is ceftazidime administered?
IV and IM
What is ceftazidime used to treat?
Difficult-to-treat
Pseudomonas
sp
Name the antibiotic in the 4th Generation of cephalosporins.
cefepime
What is the newest cephalosporin agent?
cefepime
True or False
Cephalosporins can alter the effectiveness of oral contraceptives.
True
False
True
Should cephalosporins be given with or without food?
With food to decrease GI upset, but this does delay absorption
What s/s should you monitor for after administration of cephalosporins?
(4)
Fever
Diarrhea
Bloody stools
Abdominal pain
If patient has allergic reactions to _______, it is also likely they may have allergic reactions to cephalosporins as well.
Penicillins
Author
Samilou
ID
73112
Card Set
Cephalosporins
Description
Cephalosporins
Updated
2011-03-15T20:55:02Z
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