Nursing

• Blocks synthesis of thyroid hormones - T3 -T4
• Watch for hypothyroidism
• Given by mouth
• Watch for rash, agranulosis, rash, nausea, vomiting.

Blocks Synthesis of thyroid hormone. More toxic than PTU, watch for rash and other symptoms as for PTU.

• Supresses release of thyroid hormone.
• Given 1 hour after PTU or methimazole.
• Watch for emema, hemmorhage, GI upset. Used in prep for thyroidectomy and thyroid crisis. Reduces vascularity of gland to make surgery safer.

• Supresses release of thyroid hormone. Discontinue for rash. Watch for signs of toxic iodinism.
• Used in prep for thyroidectomy and thyroid crisis. Reduces vascularity of gland to make surgery safer.

• Surpresses release of thyroid hormone. Mix with milk or juice and provide straw to avoid staining teeth.
• Used in prep for thyroidectomy and thyroid crisis. Reduces vascularity of gland to make surgery safer.

Surpresses release of thyroid hormone. Monitor input and output. Monitor glucose. May cause hypertension, nausea, vomiting, anorexia, infection.

Monitor caridac status. Hold for bradycardia, use with caution with patients in heart failure.

• Yes. It takes several weeks for symptoms to subside. Maintanance dose must be established.
• Medication sensitization, fever, rash, urticaria, agranulosis and thrombocytopenia can develop.If pharengitis fever or mouth ulscers occur, STOP MEDS AND CONTACT MD! No nasal decongestants.

No.

• Acetehexamide (Dymelor) - No longer in US
• Chlorpropamide (Diabinase)
• Tolazamide (Tolinase)
• Tolbutamide (Orinase)
• Will not see these meds very much

• Glipzide(Glucotrol, Glucotrol XL), Glyburide(Micronase, Glynase, Dia-Beta), Glimepiride(Amaryl)
• They work in pancreas stimilating beta cells
• Risk for hypoglycemia
• When taking with Beta-Andrenic Blockers, could hide hypoglycemia

• Glipzide(Glucotrol, Glucotrol XL), Glyburide(Micronase, Glynase, Dia-Beta), Glimeperide(Amaryl)
• These work in liver inhibiting production of glucose and increases sensitivity to insulin.
• Lactic Acidosis and renal failure can occur with use of iodinated contrast agents. Suspend med 48 hrs before and after testing.

• Acarbose(Precose), Miglitol(Glyset)
• Delays absorption of complex carbs in intestine and slows entry of glucose into systemic circulation.
• GI side effects- abdominal discomfort, distention, diarrhea, flatulence.
• MUST TAKE WITH FIRST BITE OF FOOD!

• Regalindine(Prandin), Nateglinide(Starlix)
• Stimulates pancreas to secrete insulin
• S/E are hypoglycemia and weight gain
• Should be taken only if eating immediately

• Pioglitazone(Actose), Rosiglitazone(Avantia)
• Sensitizes body to insulin
• S/E Hypoglucemia, Anemia
• Must be monitored by MD, causes strokes

• Sitagliptin(Januvia), Vildagliptin(Glavus)
• Increases and prolongs the action of Incretin (increases insulin release and decreases glucogon)
• Upper respiratory infection
• Admin once a day

• Lispro(humalog) 10-15min,Aspart(Novalog),Gluisine(Apidra)5-15min
• Peak 1h/40-50min/30-60min
• Duration 2-4h/2-4h/2h
• Used for quick reduction of glucose levels to treat post prandial hyperglyciemia

• Regular(Humalin R, Novalin R, Illetin 2 Regular) Onset 1/2-1H, Peak 2-3 hours, Duration 4-6 H.
• Administered 20-30 mins before meals. Can be taken alone or with a longer acting insulin.

• NPH(Neutral Protamine Hagedorn)
• Onset-2-4h Peak-4-12h duration 16-20h
• (Humalin N, Iletin 2 NPH, Novalin L [lente], novalin N [NPH])
• Onset 3-4h Peak 4-12h duration 16-20h
• Usually taken after food

• Glargine(Lantus), Detemir(Levemir)
• Onset 1h, no peak-continuous, Duration 24 hours
• Used as basal dose