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Hormones and their Actions
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ACTH
adrenal growth and steroid production
alpha-MSH
Melanin dispersian in amphibians; Learning and sexual behavior; Growth and function of testicular sertoli cells
beta-LPH
Lipolysis and fatty acid mobilization
beta-Endorphin
Analgesia; Behavior (feeding, emotion, learning); Temperature and blood pressure regulation; COntraction of reproduction tract muscles
N-terminal fragment
Potentiation of ACTH action on steriodogenesis fragment
Graves disease (hyperthyroidism)
Ab stimulates TSH receptor
Acanthosis Nigrans (insulin resistant)
Ab blocks insulin binding
Myasthenia gravis
Ab enhances turnover of Ach receptor
Asthma
Ab blocks beta-adrenergic binding receptor
Congenital nephrogenic diabetes insipidus
ADH (vasopressin) receptor deficiency
Pseudohypoparathyroidism
PTH receptor deficiency
Obesity
Insulin binding decreased
Diabetes mellitus type II. SOme forms of NIDDM
Insulin binding decreased cus receptor is downregulated.
Diabetes mellitus type I
Deficiency of insulin
Dwarfism
Deficiency of growth hormone
Gigantism, acromegaly
Excess secretion of growth hormone
Familial neurohypophyseal diabetes insipidus (FNDI)
Mutations in ADH (vasopressin) prohormone decrease VP synthesis
G-as
beta-adrenergic amines; glucagon; PTH ------> Stimulates adenylate cyclase
G-ai
acetylecholine; alpha-adrenergic amines -----> Inhibits adenylate cyclase
G-at
photons -----> stimulate cGMP phosphodiesterase
G-aq
acetylecholine; alpha-adrenergic amines -----> increase IP3 and intracellular Ca2+
G-a13
Thrombin -----> Stimulate Na+ and H+ exchange
Author
Anonymous
ID
72343
Card Set
Hormones and their Actions
Description
Biochem lectures 55-56
Updated
2011-03-12T02:57:55Z
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