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1. What protozoal organism can be identified by horizontal or zig-zag movement?
Ans. Spironucleus muris pg. 99
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2. Mice infected with Spironucleus muris have increased sensitivity to?
Ans. Irradiation pg. 99
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3. Name a non-pathogenic protozoal organism found in the cecum, colon, and small intestine of mice, rats, and hamsters?
Ans. Tritrichomonas muris pg. 99
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4. What is the name of the organism that causes renal coccidiosis in mice and has a �honey-combed� appearance on histopath?
Ans. Klosiella muris pg. 99
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5. Cryptospiridium _____ adheres to the gastric mucosa and Cryptospiridium _____inhabits the small intestine?
Ans. muris, parvum pg. 99
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6. What organism causes entamoebiasis in the cecum and colon of mice, rats, and hamsters?
Ans. Entamoeba muris pg. 99
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7. Name a gram + microsporidian that infects most common lab animals but is rare among lab mice?
Ans. Encephalitozoon cuniculi pg. 99
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8. E. cuniculi shed spores in the?
Ans. Urine pg. 99
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9. E. cuniculi stains well with what stains?
Ans. Good pasture, Giemsa, and Gram
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10. Fulminating infection of E. cuniculi can affect which organs?
Ans. Kidneys, liver, brain pg. 100
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11. The mouse serves as an intermediate host for what gram neutral, zoonotic, coccidian parasite?
Ans. Toxoplasma gondii pg. 100
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12. What is the only cestode that does not require an intermediate host?
Ans. Rodentolepsis nana pg. 100
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13. R. nana can be differentiated from R. diminuta by the presence of ?
Ans. Rostellar hooks and polar filaments pg. 100
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14. Mice are an intermediate host for the cat tapeworm called?
Ans. Taenia taeniaformis pg. 100
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15. The mouse pinworm that also infects rats, gerbils, and hamsters is?
Ans. Syphacia obvelata pg. 100
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16. Syphacia obvelata has a life cycle of ____ days and is infective in___?
Ans. 11-15 days, 6 hrs pg. 101
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17. The life cycle of Syphacia muris is ____ days?
Ans. 7-9 pg. 101
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18. Aspicularis tetraptera is infective in _____ days and has a life cycle of ____ days?
Ans. 6-7 , 23-25 pg. 102
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19. A. tetraptera is diagnoised by ______ and S. obvelata is diagnosed by _______?
Ans. fecal float, cellophane tape test pg. 102
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20. What is the genus and species of the tropical rat mite?
Ans. Ornithonyssus bacoti pg. 102
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21. Myobia, Radfordia, and Psoregates belong to what suborder, while Myocoptes belongs to the suborder______?
Ans. Prostigmata, Astigmata pg. 102
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22. ______ _____ forms keratotic cysts during infestation.
Ans. Psorergates simplex pg. 103
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23. _____ has a single tarsal claw on the 2nd pair of legs, whereas _____ has two claws of unequal size on the terminal tarsal structure of its second pair of legs.
Ans. Myobia, Radfordia pg. 103
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24. What is the most common ectoparasite of the lab mouse?
Ans. Myocoptes musculinus pg. 104
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25. Chronic acariasis may provoke what condition due to long-standing dermatitis?
Ans. Secondary amyloidosis pg. 105
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26. Amyloidosis is diagnosed by?
Ans. Apple green birefringence under polarized light when stained with Congo red pg. 105
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27. Mineralization of the myocardium and epicardium is common in what 3 strains of mice?
Ans. BALB/c, DBA, C3H pg. 106
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28. A Reye�s-like syndrome has been reported in what strain of mice?
Ans. BALB/c pg. 106
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29. A deficiency of what vitamin causes tremors, diarrhea, rough hair coat, keratitis, poor growth, abscesses, hemorrhages, and sterility or abortion?
Ans. Vit. A pg. 106
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30. A deficiency of what vitamin causes muscular dystrophy and hyaline degeneration?
Ans. Vit. E pg. 106
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31. A deficiency of what vitamin causes alopecia, decreased feed consumption, poor growth, poor reproduction and lactation and neurological abnormalities?
Ans. Vit. B complex pg. 106
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32. Mice have an absolute requirement for a dietary source of what essential fatty acids?
Ans. Linoleic and Arachadonic acid pg. 107
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33. Black mice are prone to what skin condition?
Ans. Ulcerative dermatitis pg. 107
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34. What condition is associated with low relative humidity and causes constriction of the tail and occasionally of the feet and digits?
Ans. Ringtail pg. 108
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35. Males of what strain are notorious for fighting?
Ans. BALB/c pg. 108
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36. Atrial thrombosis has a high prevalence in what strain of mice?
Ans. RFM pg. 108
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37. What strain of mice develops immune complex glomerulonephritis as an autoimmune disease?
Ans. NZB and NZB x NZW F1 pg. 109
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38. Immune complex glomerulonephritis can be caused by what virus?
Ans. LCMV pg. 109
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39. What strain of mice express the rd gene, which leads to retinal degeneration within the first few weeks of life and has been used extensively as a model of retinitis pigmentosa?
Ans. C3H/He pg. 110
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40. What strain of mice commonly exhibits microophthalmia?
Ans. C57BL/6 (note)
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41. Viruses associated with lymphopoietic and hematopoietic neoplasia belong to what family and what type?
Ans. Retroviridae, Type C oncornavirus pg.111
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42. What is the most common malignancy in the mouse and where does it originate?
Ans. Lymphoblastic leukemia, thymus pg.111
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43. What is the term for organs that appear green in older mice affected with myelogenous leukemia?
Ans. Chloroleukemia pg.111
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44. What is another name for MMTV-S and how is it transmitted?
Ans. Bittner virus, through milk pg.112
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45. What strains of mice have a high natural prevalence of mammary tumors?
Ans. C3H, A, DBA/2 pg.111
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46. Primary respiratory tumors of mice occur in relatively high frequency, 95% of these are of what type?
Ans. Pulmonary adenomas pg.113
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47. From what 2 types of cells do pulmonary adenomas arise?
Ans. Type II pneumocytes and Clara cells pg.113
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