Bluebook questions Ch 3 83-99.txt

1. What is the etiological agent of rolling disease?

2. Rolling disease is associated with experimental inoculation or?

3. CAR bacillus in rats produces clinical disease and lesions that closely resemble?

4. In mice, CAR bacillus is an __________ ______________?

5. Diagnosis of CAR bacillus uses __________ ___________ to visualize argyrophilic bacilli adherent to the ______________ membranes of bronchial respiratory epithelium?

6. Tyzzer�s disease is caused by ______________ _______________ and was first diagnosed in? (p 83)

7. What is required for in vitro growth of Tyzzer�s disease?

8. Name three diagnostic stains used for Tyzzer�s disease?

9. The causative agent of Transmissable Murine Colonic Hyperplasia is?

10. Surprisingly Citrobacter rodentium does not utilize _________?

11. The characteristic gross finding of Citrobacter rodentium is?

12. Attachment to the mucosa of the colon is accompanied by ____________ of the microvillus border and formation of __________ structures?

13. Transmissable Murine Colonic Hyperplasia must be differentiated from other diarrheal diseases of mice. What are they?

14. Colonic hyperplasia due to Transmissable Murine Colonic Hyperplasia has been shown to increase the sensitivity of colonic mucosa to?

15. Pseudomonas infection is not part of normal flora and infections are almost always silent except in?

16. Pseudomonas aeroginosa carrier mice can be detected by?

17. Pasteurella pneumotropica may complicate pneumonias due to?

18. Pasteurella pneumotropica should be excluded from colonies that contain?

19. Name the six species of Helicobacter that infect mice?

20. Helicobacter organisms are most commonly ureas ____, catalase _____, and oxidase _____?

21. H. hepaticus can cause inflammatory bowel disease, which may present as _________ and/or diarrhea?

22. H. hepaticus can persist in the GI tract, particularly?

23. What strain of mice infected with H. hepaticus show elevated liver enzymes?

24. Helicobacter spp. colonize which portion of the GI tract?

25. Which Helicobacter spp. are associated with hepatomas and hepatocellular carcinomas and what sex and strains of mice are involved?

26. An increase in hepatic haemangiosarcoma due to H. hepaticus has been noted in?

27. What strains of mice are resistant to H. hepaticus hepatitis?

28. What strains of mice are susceptible to H. hepaticus hepatitis?

29. PCR does not differentiate Helicobacter spp. What method is used for molecular speciation?

30. What treatment regimen has been used to successfully treat Helicobacter infection?

31. What is the genus and species for the disease Salmonellosis?

32. Salmonella enteritidis is a gram-negative rod that rarely ferments?

33. What nutritional deficiency has an attenuating effect on Salmonella infection in mice and how does it appear to promote bacterial growth and enhance virulence?

34. What Salmonella organism has been associated with chronic arthritis?

35. _______________ lesions are particularly characteristic of chronic salmonellosis, especially of the liver?

36. What tissue for culture may be more reliable for detecting Salmonella?

37. Streptobacillus moniliformis is known to cause?

38. Streptobacillus moniliformis has an affinity for?

39. Which Corynebacterium spp. has been associated with hyperkeratosis?

40. Corynebacterial keratoconjunctivitis has been reported in which strain of mice?

41. Which Corynebacterium spp. is associated with cervical lymphadenopathy and arthritis?

42. Hyperkeratosis due to C. bovis is typically more severe in ________ mice than in ______mice?

43. Which species of Staphylococcus is nonpathogenic?

44. Pathogenic staphylococci are typically coagulase ___?

45. Which Staphylococcus is coagulase-negative?

46. Which strains of mice are most susceptible to Staphylococcus spp.?

47. Most streptococcal infections in laboratory mice are caused by what

48. What Streptococcus spp. has been isolated from visceral abscesses of immunocompetent mice?

Infection with ?�hemolytic streptococci can cause inflammatory lesions affecting _________ and __________?

49. E. coli must be differentiated from?

50. Name the two Klebsiella organisms found in mice?

51. Name the two mycobacteria known to be pathogenic for laboratory mice?

52. Which species of mycobacteria has been a historical model for human leprosy?

53. What is the histologic hallmark for M. lepraemurium?

54. What organ is commonly affected by Proteus miribilis?

55. Name the genus, species and serovar of Leptospirosis that has been reported on several occasions in laboratory mice?

56. The primary natural vector of Eperythrozoon coccoides is?

57. Eperythrozoon coccoides can be transmitted to mice from contaminated?

58. How is Eperythrozoon coccoides diagnosed?

59. Eperythrozoon coccoides potentiates coincidental viral infections in mice. Name three agents that demonstrate this?

60. Nigg agent is thought to be responsible for a noteworthy infection in mice. What infectious agent is it associated with?

61. Chlamydia trachomatis produces what type of inclusion bodies?

62. Pneumocystis carinii is a significant disease threat to?

63. Pneumocystis carinii is clinically severe in immunodeficient mice because they are lacking in what cell?

64. Gross lesions of Pneumocystis carinii are?

65. What is the most common fungal agent of mice?

66. Describe the appearance of Giardia muris?

67. Giardia muris infects the __________ of _______, _______, and __________?

68. Giardia muris organisms can be recognized on wet mounts by what characteristic movements?

69. Describe the appearance of Spironucleus muris?

70. Spironucleus muris infects the __________ of _______ and __________?

71. Spironucleus muris organisms can be recognized on wet mounts by what characteristic movements?

72. What protozoal organism that infects mice, increases sensitivity to irradiation?

73. Tritrichomonas muris resides in the ________, ________, and _______ _________?

74. Tritrichomonas muris affects _______, ________, and _________?

75. Name the coccidial agent that occurs in the epithelial cells of the large intestine of mice?

76. Name the agent that causes renal coccidiosis?

77. Entamoeba muris resides in the ________ and _________?

78. Entamoeba muris affects _______, ________, and _________?

79. Encephalitozoon cuniculi affects what species?