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What gases are diffusion limited?
CO, O2
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What gases are perfusion limited?
- Niitrous oxide (N20), O2 (more common pefusion than diffusion)
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What causes O2 to switch from perfusion to diffusion-mediated?
- Diffusion capacity decreases
- Fibrosis causes thickness to increase, so less oxygen can get through and the time to get through increases
- Partial Pressure is maintained throughout capillary
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If the molecular weight drops and solubility increases, what happens to Diffusion coefficient?
- It will increase
- **This means that the specific gas will be more readily absorbed
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What does body size, gender and age do to diffusion capacity (DL)?
- Body size = increase
- Gender = Male = increase
- Age = decrease
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What are the three methods of gases being used in the body?
- Dissolved: Nitrogen
- Bound : O2 to Hgb
- Modified: CO2 to HCO3-
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