Immuno #2.txt

After creation in the Bone marrow, where do the B and T-cells go for maturation?
- B: Bone Marrow
- T: Thymus
What T-cell is different by increasing with age?

T_c (cytotoxic b/c there are more tumors and cancers to take care of later in life)
What are the four secondary lymph tissues?
- Lymph nodes
- Spleen
- MALT
- Tonsils
What is the main function of the lymph node?

Filter lymphocytes and help present antigens for activation
What secondary lymph organ filters blood?

Spleen
What is the difference b/t Red and white pulp in the spleen?
- Red = RBC phagocytosis
- White = lymphatics
What 3 areas do the tonsils filter?

Nasal, oral, pharyngeal
What happens to CD4 T-cells as the thymus ages?

Production decreases
How do lymphocytes enter and leave the Lymph nodes?
- Enter via HEV
- Leave via Efferent lymphatic vessels
How do DC enter the lymph nodes with antigens?

Afferent lymphatic vessels
Are the lymphatics and blood independent of one another?

No
What are the components of extravasation that allow a lymphocyte to dock?
- CAMS:
- 1) Integrins
- 2) Selectins
Which is more limited, B or T-cell migration?

T-cell

Author

kepling

71728

Card Set

Immuno #2.txt

Description

Immuno #2

Updated

2011-03-22T18:37:31Z

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