pharmacology

t/f antibiotics are given before a tooth is worked on to get rid of the infection
True False

Antibiotics are used in dentistry to treat ______ infection

how long must you premed for a joint replacement?

as a dental hygienist what is our role in antibacterial therapy? 4

what is it called when the normal flor becomes pathogenic

what is it called when there is a proliferation of transient microoganisms?

t/f autogenous infections occur when there is a proliferation of transient microorganisms
True False

the common thread in pharmacologic strategies is to target differences between _______, (bacterial) and _____ (host or body) cells.

t/f eukaryotic cells are bacterial cells
True False

are prokaryotic cells bacterial or host cells?

what is a unique target for antibacterial thearpy? why doesn't this effect the host cells?

what are the three rules for antibacterial drug selection

by the time antibacterial agnets are indicated what is seen in the host? (signs for giving antibiotics)

t/f gram - bacilli predominate during infection
True False

what is described: reduction of number of normal flora, broad spectrum cause opportunistic infection, non susceptible microbes flourish

t/f you want to pick the most broad spectrum drug to fight infection
True False

t/f bactericidal drugs slow the growth of bacteria
True False

is it bacyericidal or bacteriostatic if it slows the growth of bacteria

what is it called when larger amounts of antibiotic are given to get a higher blood level all at once

t/f oral infections are all gram positive
True False

is a granuloma chronic or acute

a chonic infection is more _____ for the anaerobes

with a chronic infection bacterial species ____ and selective ______ survive

with a chronic infection the microbiology is more ____ than acute

t/f chronic infections are poorly localized
True False

successfull treatment of an infection is based on the debridement and the _______ immune system

if you have an immunocompromised pt what is used along with the debridement to treat infection?

if the ______ function is suppressed it can adversely affect the therapeutic outcome, they can be adversely affect by a variety of diseases and by meds such as _______ therapy

with a reduced immune response a ______ antibiotic may need to be used instead of a ______

what are some examples of bactericidal drugs?

what is the action of a bactericidal drug?

what drug is a DNA synthesis inhbitor in aneorbes?

what are some examples of bacteriostatic drugs

t/f immunocompetent hosts need to have bacteriocidal drugs and immunocompromised need bacteriostatic drugs

bacterial cell wall inhibitors that are the most important are ______ and _____-______

what are the drugs of choice for antibacterial prophylaxis

what is recommended if a beta-lactam allergy exists?

what is the prototype for the penicillin class?

how is penicillin G administered?

what was the first oral doseform of penicillin?

what is the most common agent used today for penicillins?

what was added to penicillin to enhance absorption?

t/f penicillin VK is bactericidal
True False

what iss associated with a non allergic rash with pt with mononucleosis

what is the most commonly prescribed anitbacterial drug in dentistry

t/f penicillin is safe to give to pregnant women
True False

amoxicillin + _____ ______ = augmentin

what is added to some penicillins to make resistant to penicillinase?

what is the prototype penicillinase resistant agent?

what is used when an organism releases penicillinase and degrades penicilllin molecules

what antibiotic prophylaxis is used for a pt with TJR

t/f cephalexin is a first line agent used for antibiotic prophylaxis for individulas with TJR
True False

Cephalosporins are structurally related to _____

what drug is used for periodontal infection (gram negative)

metronidazole is effective against _____ _____

are the inhibitors of transcription or trnaslation of RNA bacteriostatic or bacteriocidal?

what binds to the 50S ribosomal subunit?

what are the agents that bind to 30S ribosomal subunit

all of the following antibacterial agents are condsidered bacteriostatic except:
A. cephalosporin
B. doxycycline
C. clindamycin
D. minocycline
E. erythromycin

what are the three explanations for biofilms resistance to antibacterial agetns?

t/f the bacteria are more susceptible to antibiotics when they are in their planktonic form rather than in biofilm
True False

once in biofilm bacteria are protected against _____ by PNMS (neutrophils)

biofilm drug resistance is related to the slow and _____ penetration of ______ agents into biofilm

when taking the antibiotics you should instruct the pt to take agent ____ minutes before or ____ hours after a meal

what foods should tetracycline not be taken with?

why shouldn't tetracycline be taken with calcium?

t/f amoxicillin, pen VK, metronidazole, azithromycin and clindamycin are affected by food
True False

which of the following antibacterial agents is structurally realted to penicillin?
A. erythromycin
B. metronidazole
C. aminoglycocides
D. tetracycline
E. cephalosporins

is aminioglycocides baceriostatic or bacteriocidal?

is cephalosporins bacteriocidal or bacteriostatic?

is erythromycin bacteriostatic or bacteriocidal?

is metronidazole bacteriocidal or bacteriostatic

is tetrcycline bacteriostatic or bacteriocidal

t/f erythromycin is a macrolide?
True False

t/f cephalosporins is a beta lactam and is structurally realated to penicillin
True False