21 musculoskeletal and Antiinflammatory

two broad categories of drugs used to treat disorders of the musculoskeletal system

medication used to treat some musculoskeletal disorders associated with pain, spasm, abnormal contraction or impaired mobility

true or false

muscle relaxants are given on a long term basis
True False

muscle relaxant drugs affect the _______ and ______ with no direct effect on skeletal muscle

muscle relaxants produce a ______ effect promoting rest and relaxation

two drugs used to treat acute, painful musculoskeletal conditions include:

a different type of muscle relaxant that causes a direct effect on skeletal muscles and manages spasticity from upper motor neuron disorders

two upper motor neuron disorders

this relaxant acts on the muscle itself and is not intended for use if caused by trauma

neuromuscular blocking agents are used for what?

succinylcholine and rocuronium (zemuron) are what types of muscle relaxants

the major muscle of ventilation is the _____

NMBA's are potentially very dangerous and can result in respiratory arrest because of the potential to _________ the diaphragm

who can administer NMBA's?

an antidote for NMBA's is:

_______ can also be used to treat myasthenia gravis

skeletal muscle relaxant side effects

the appropriate care for musculoskeletal injuries (acronym)

______ drugs are used to treat disorders in which the musculoskeletal system is not functioning properly due to inflammation

examples of conditions that require anti-inflammatory drugs

can NSAIDS be given for lengthy time periods?

the oldest drug in the NSAID category

anti inflammatory drugs that do not inhibit clotting and cause fewer gastric problems and less GI bleeding than other NSAIDS

an example of an NSAID that inhibits COX-2 and has the potential to cause fewer gastric problems and pose less risk of GI bleeding

these are side effects of ________

GI ulceration and bleeding
Epigastric pain
GERD
myocardial infarction
fluid retention
hematuria
rash

these are contraindications with

NSAIDS should be given with what to reduce GI side effects

a metabolic disorder characterized by accumulation of uric acid crystals in various joints, especially the big toe, ankle, knee, and elbow with resultant pain and swelling

side of effects of gout meds

what should be encouraged to facilitate excretion of uric acid crystals?

______ is a specific drug that is used to relieve inflammation in acute gouty arthiritis

a disease characterized by low bone mass and deterioration of bone tissue, leading to bone fragility and increased susceptibility to fracture, especially to the hip, spine, and wrist

osteoporosis effects the older population but primarily who?

osteoporosis therapy include:

bone loss occurs with the first ___ years after the onset of menopause

nonhormonal agents that act directly to inhibit bone reabsorption, thereby increasing bone mineral density at the spine and hip as well as decreasing the incidence of first and future fractures

first line therapy bisphosphonates approved for prevention and treatment of osteoporosis (3)

a chronic disorder characterized by fractures, skeletal abnormalities, and significant bone pain

bisphosphonate side effects

these are contraindications for ______

hypocalcemia
renal failure
inability to sit upright for 30-60 mins

should bisphosphonates be taken after the first meal?