-
-
Inhibitors P450
(3)
- -Macrolides except Azith, Dirith
- -Quinolones
-2D6
-
Inducers CYP3A4
(1)
-Nevirapine
-
Inhibitors CYP3A4
(4)
- -Streptogramins
- -Ketolides
- -Azoles
- -Ritonavir
- -Bis(chloroethyl)amines
-
Depolarize the cell membroane
(2)
- -Cyclic lipopeptides
- -Televanacin
-
Cross-links DNA
(2)
- -Mitomycin-C
- -Cyclophosphamide
-
Prolonged Q-T
(2)
- -GnRH-ANAagonists
- -Ketolides
-
Biphosphorylation via human kinases
(2)
-
-
IOPS
30s
50s
30s-all Broad, ONLY CIDAL is Aminoglycosides
50s-ONLY 2 CIDAL are Steprogramins and Ketolides
-
-
-
AF
Sulfa-Static
Trimethopril-Cidal
-
Anti-TB
Primary
Secondary
Primary-Cidal EXCEPT Ethambutol
Secondary-Static
-
SASI
PE-Cidal (Polyenes, Echinocandins)
AF-Static (Flucytosine, Azoles)
-
SAMI
All Static except Allylamines can be CIDAL against Dematophytes
-
-
-
NP
All CCS EXCEPT CAM(CAmptothecins, Anthracycliens, Mitomycin)
-
Chelation
- -Tetracyclines
- -Quinolones
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