MED-Ondansetron

Anti-emetic

A serotonin receptor antagonist that prevents acute emesis by blocking serotonin receptors in the chemoreceptor triggering zone (CTZ) and afferent vagal neurons in the upper GI tract. It does not have prophylactic properties and therefore has no effect on delayed emesis. Does not cause extrapyramidal symptoms

Acute N/V

Known hypersensitivity

Use cautiously with other drugs that prolong the QT interval

Headache, diarrhea, dizziness, fever, drowsiness, prolonged QT

May form precipitate with alkaline solutions

Adult: 4 mg slow IV/IM, may repeat once after 10 mins

Pedi: 0.1 mg/kg (max single dose 4 mg)