-
sympathetic or adrenergic nervous system
fight or flight system
-
parasympathetic or cholinergic system
rest and restore system
-
seizure
period of altered brain function due to recurrent abnormal electrical impulses
-
status epilepticus
ongoing seizures
-
anticonvulsant drugs
used to help prevent seizures
-
tranquilizers (benzos)
drugs used to calm animals and reduce anxiety and aggression
-
sedatives (barbs)
drugs used to decrease irritability and excitement in animals
-
anti-anxiety
used to lessen anxiousness but do not cause drowsiness
-
SSRIs (SelectiveSerotonin Reuptake Inhibitors)
serotonin regulates emotion, anxiety, agitation and sleep
-
TCAs (Tricyclic Antidepressants)
work to increase availability of serotonin, used to treat separation anxiety and behavior problems
-
acepromazine, prochlorperazine (Compazine)
phenothiazine drugs
-
Compazine
GI problems with sedative effect, antiemetic
-
xylazine (Rompun), dexmedetomidine (Dexdomitor)
Alpha-2 agonist drugs
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Alpha-2 Agonists
Profound cardiovascular effects, cats will vomit, slows insulin resulting in hypergylcemia, sed and analgesic in minor surgeries
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analgesics
drugs used to provide pain relief
-
narcotic (opioid) agonists
drugs typically used to treat moderate to severe pain
-
narcotic receptors
mu, kappa, delta, sigma, and epsilon
-
antitussive, antidiarrheal, pre and post anelgesic and sedative
narcotic agonist uses
-
narcotic (Opioid) antagonists
drugs that block the binding of opioids to their receptors
-
morphine, meperidine, hydromorphone, butorphanol, buprenorphine, fentanyl, codeine
narcotic drugs
-
meperidine
Demerol, less than 2 hr duration, less side effects than morphine, used for acute pain
-
Torbutrol, Torbugesic
butorphanol, mild pain, mild sedation, ANTITUSSIVE
-
Buprenex
buprenorphine, moderate pain, less vomiting and salivation, good with cats transmucosal
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tramadol (narcotic-like)
Ultram
-
Narcan (narcotic antagonist)
naloxone
-
anesthetics
drugs used to produce loss of sensation, muscle relaxation and or loss of consciousness
-
general anesthetics
affect CNS and produce loss of sensation with partial or complete loss of consciousness
-
local anesthetics
block nerve transmission in the area of application and produce loss of sensation without loss of consciousness
-
sevoflurane, SevoFlo
inhalant anesthetic drug, metabolized by lungs not liver
-
CNS stimulants
drugs used to reverse CNS depression
-
pentobarbital sodium (Sleep away and Beuthanasia D) and Fatal-Plus
euthanasia agents
-
inflammation
process that can occur in the body in response to tissue damage
-
fever
increase of body temperature above normal, helps fight disease by destroying foreign invaders
-
pain
an unpleasant sensation that is usually associated with tissue damage
-
anti-inflammatory
drug that prevents or reduces inflammation
-
antipyretic
drug that prevents or reduces fever
-
analgesic
drug that prevents or reduces pain
-
histamine
chemical substance that triggers an inflammatory response
-
antihistamine
drug that inhibits the release of histamine
-
Iatrogenic
condition caused by treatment ordered by vet
-
glucocorticoids, non-steroidal anti-inflammatory drugs, antihistamines and muscle relaxants
4 groups of drugs to control inflammation
-
hormone
chemical substance produced in one part of the body that is transported to another part of the body where it influences and regulates cellular and organ activity
-
corticosteroids
hormones produced in the adrenal cortex of the adrenal gland
-
glucocorticoids, cortisol is the main form
have an anti-inflammatory property, used to treat systemic disease such as cancer and Addison's and allergic responses
-
Addison's
hypoadrenocorticism, too little steroids in the body
-
minerocorticoids, Aldosterone
helps the body retain Na and H2O
-
pruritis, anaphylaxis
itching, life-threatening allergy
-
cyclooxygenase
non-steroidal anti-inflammatory drug NSAIDS
-
cox-1
more involved with stomach, will see GI irritation
-
cox-2
more involved with inflammation
-
melena
black, 'tarry' feces
-
antacids
when using NSAIDS do not administer _____ because they can affect the absorption of other drugs
-
aspirin
use with caution in cats as very susceptible to overdose due to inability to metabolize rapidly
-
phenylbutazone (bute)
primarily used in horses (NSAID)
-
DMSO
anti-inflammatory that is used as a carrier for other drugs, garlic taste in the mouth and skin irritation, penetrates skin (NSAID)
-
Adequan
used in dogs and horses to promote healing of synovial membrane (NSAID)
-
glucosamine/chondroitin
used primarily for osteoarthritis to aid in maintaining cartilage structure and function (NSAID)
-
carprofen (Rimadyl)
in dogs relieves inflammation and pain associated with degenerative joint disease (COX-2 NSAIDS) beefy taste
-
EtoGesic
once a day dosing or in dogs an anti-inflammatory and analgesic for osteoarthritis (COX-2 NSAID)
-
Deramaxx
used in dogs to treat pain and inflammation associated with orthropedic surgery and osteoarthritis (COX-2 NSAID)
-
Metacam
dogs and cats used to treat pain and inflammation associated with osteoarthritis and surgery and to reduce fever. Available in oral suspension (COX-2 NSAID)
-
Zubrin
dogs to treat acute and chronic pain and inflammation of osteoarthritis and surgery, dissolvable tablets (COX-2 NSAIDS)
-
pruitis, allergic reactions, motion sickness, anaphylactic shock
clinical uses for antihistamines
-
diphenhydramine (Benadryl)
antihistamine, alergy pill and injectable
-
chlorpheniramine
antihistamine
-
methocarbamol (Robaxin-V)
used to treat pain associated with muscle spasms and toxic injestions (cig butts)
-
-
chemoreceptor trigger zone CRTZ
detects chemical changes and will respond by stimulating the activation of the vomiting center
-
dopamine
neurotranmitter for the chemoreceptor trigger zone
-
acetylcholine
neurotransmitter for the vomiting center
-
centrally acting drug
affect the vomiting center in the medulla of the brain (emetic drug)
-
local acting drugs
action is induced in the stomach directly (emetic drug)
-
apomorphine
central acting emetic drug, morphine derivative to induce vomiting in dogs, administered in conjunctival sac
-
xylazine (Rompun)
central acting emetic drug, used to induce vomiting in cats
-
hydrogen peroxide
used to induce vomiting, home remedy, local acting emetic
-
procainamide derivative
used to treat parvovirus enteritis, type of anti-emetic
-
vestibular disturbances
inner ear abnormalities that cause balance problems
-
prochlorperazine (Compazine)
used to treat vomiting, GI diarrhea and motion sickness, phenothiazine
-
metoclopramide (Reglan)
gets things moving through GI tract, do not use with obstructions, procainamide
-
diphenhydramine (Benadryl)
motion sickness and vestibular disease
-
ulcers
areas of mucosal erosion
-
antacids
promote the healing of ulcers by neutralizing HCl
-
histamine blockers
work by blocking histamine receptors on cells that line the stomach which reduces gastric acid secretion
-
mucosal protectants
work by coating and protecting ulcers from stomach acid
-
prostaglandin synthetics
work by surpressing gastric secretions and increasing mucus production
-
proton pump inhibitors
work by binding certain enzymes on the surface of stomach cells so that the cell cannot secrete HCl
-
Amphogel
binds with phosphorus so may also be useful in renal failure, antacid
-
famotidine (Pepcid)
more potent and fewer side effects that Zantac, histamine blocker
-
antidiarrheal
drug that decreases peristalsis of the GI tract
-
anticholinergics, opiate-related drugs, absorbents and protectants, probiotics and antibiotics
categories of drugs used to treat or prevent diarrhea
-
laxatives (cathartics, purgatives
drugs that increase fluid content of feces that results in softened feces for easier passage
-
osmotic laxatives
hold water in gastrointestinal tract to increase moisture content of stool
-
bulk laxatives
absorb water and expand to provide increased bulk and moisture content to stool
-
lubricants
make stool slippery
-
emollients
reduce water tension of stool, allowing water to enter
-
irritants
irritation causes increased motility (bowel emptying)
-
cholinergics, serotonergic
GI stimulant categories
-
degestive enzyme drug
pancreatic enzyme supplements that are used to treat exocrine pancreatic insufficiency.
-
Slentrol
weight loss drug
-
CET products
pastes, sprays, chews etc. with various active ingredients and flavors, should not be rinsed out
-
Nolvadent, Oraldent
cleansing oral rinses
-
Hills T/D Diet
food that helps prevent tartar buildup
-
Doxirobe
gel placed in periodontal pockets after dental cleansing that releases an antibiotic for several weeks
-
nebulization
process of converting liquid medications into a spray that can be inhaled
-
reverse sneeze
short periods of noisy respiratory effort in drops
-
expectorant
drug that decreases the viscosity of respiratory secretions
-
mucolytic
drug that decreases the viscosity of repiratory secretions
-
Tussigon or Hycodan (hydrocodone)
used for harsh, non-productive coughs in dogs, controlled substance
-
Torpex, albuterol
used to treat airway diseases in horses by relieving brochospasm and bronchoconstriction (equine inhaler) brochodilator drug
-
methylxanthines
brochodilators used in repiratory and cardiac conditions, mild heart and respiratory muscle stimulus
-
aminophylline
used to treat inflammatory airway diseases in dogs, cats, and horses
-
doxapram, Dopram-V/Respiran
used to treat repiratory depression or to stimulate respirations post-anesthesia, found on the crash cart
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