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Ovary
Mesothelium: CUBOIDAL rather than sq
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Oocyte
- Oogonia goes on meiotic division = primary oocyte, arrest at prophase
- 5th fetal month = all oocytes
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Primary follicle
- oocyte enlarges
- follicular cells become CUBOIDAL
- stroma (theca) cells don't penetrate BM (now more prominent)
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Secondary (antral) follicle
- follicular cells->granulosa cells (2 types)
- Membrana granulosa- wall surrounding antrum, mural granulosa cells
- Cumulus oophorus- surrounds zona pellucida
- Theca interna- sinusoidal cap's, C19 steroid androstenedione crosses BM for conversion to estradiol by granulosa cells
- Theca externa- thin myoid-like contractile layer
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Graafian follicle
- mature follicle
- Cumulus oophorus becomes free floating
- resumes meiosis, arrested at metaphase as secondary oocyteSecondary oocyte, zona pellucida, cumulus oophorus, follicular fluid release
- Membrana granulosa=>corpus luteum
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Atresia
- fate of most follicles
- small and large atretic follicle
- hyalinization of BM= glassy membrane
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Corpus luteum
- forms from membrana granulosa
- endocrine gland
- granulosa cells-> granulosa lutein cells
- theca interna-> theca lutein cells
- W/o preg--> turns into corpus albicans
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Oviduct (Fallpian tube)
- 1. Infundibulum- high amt ciliated cells
- 2. Ampulla- longest seg, site of fertilization, high amt ciliated cells & mucosal folds, muscularis is THIN (2 layers, IC & OL)
- 3. Isthmus- narrowest seg, low folds and ciliated cells, thicker muscularis
- 4. Intramural- pierces uterine wall, opening to uterine lumen, little folding, mucularis THICKEST
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