phosphodiesterase inhibitors/miscellaneous resp drugs

phosphodiesterase are drugs that are also called

xanthines
xanthines inhibits

cellular production of phosphodiesterase
phosphodiestrerase is a enzyme that breaks down

cyclic adenosine
name a drug that is a phosphodiesterase inhibitor/xanthines

theophylline (aminophylline)
what does theophylline do

stimulates rr and depth of breathing
what does theo produces

pulm vasodilation and bronchodilation
theo is used to

decrease airwayway resistance (esp in pt with asthma)
duration of theo

4-6 hours
adverse effects of theo
- cardiac effects
- cns effects
- nausea and vomitting
- diuresis
name some misc resp drugs
- cromolyn sodium- intal
- leukotriene modifiers
- ethanol- etyhl alcohol
what is cromolyn sodium-intal stabilizes

stabilizes mast cell, making it less sensitive to specific antigens and release of histamine
cromolyn sodium-intal is used as

preventive therapy for asthma not effective during asthma attack
what happens during an asthma attack

mast cells in the airway release leukotrienes, which results a inflam response (bronchoconstriction, mucus production, and vascular permeability)
leukotrine modifiers prevents

inflam response from occuring
common drugs of leukotrine modifiers are
- accolate
- singulair **
- zyflo
what is ethanol- ethyl alcohol

antifoaming agent (surfactant) used to dec the surface tension of frothy, bubbly secretions
frothy, bubble secretions are observed with

pulmunary edema

Author

Anonymous

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Card Set

phosphodiesterase inhibitors/miscellaneous resp drugs

Description

phosphodiesterase inhibitors/miscellaneous resp drugs

Updated

2011-02-23T02:17:46Z