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Pharmacology
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Pharmacokinetics
The study of what happens to a drug from the time it is put in to the body until the parent drugand all metabolites have left the body.
Nursing Process
Assessment
Nursing Diagnosis
Planning
Implementation
Evaluation
Compliance
Taking all doses of medications correctly over prescribed length of therapy
Non-compliance
Failure to follow directions
Knowledge deficit
Lack of knowledge
Placebo
an inactive (inert) substance
Auto therepy
self medication
Delegation
the transferring of responsibility for the performance of an activity or taskwhile retaining accountability for the outcome.
THE TASK IS DELEGATED NOT THE PATIENT
5 rights of delegation
Right Task
Right Circumstance
Right Person
Right Directions/Communication
Right Supervision
Absorption
Drug enters blood stream
Distribution
Drug circulates through body
Metabolism
Drug broken down into metabolites- usually in liver
Excretion
Drug eliminated from body
Serum half-life
time 1/2 drug eliminated from body - important for dosing time.
Factors affecting drug action
Age, weight, gender, dosage, route, food and drug interactions, genetics and race, pathologic conditions, psychological
Additive
Drug A & B (similuar effects)
double effect
Potentiation
Drug A & B (Different actions) greater than effect of single drugs.
More than doubled.
Displacement
Drug A displaces Drug B from plasma protein binding sites- more free drug B-
greater effect of drug B
Interference
Drug A interfers with excretion or metabolism of Drug B- Drug B
in body longer
- increase effect of Drug B
Passive Diffusion
Molecules move with the concentration gradient (greater to lesser)until equilibrium is reached
Active transport
Molecules move against the concentrated gradient
Pharmacodynamics
The study of what drug does to the body. How the drug works.
The Four Phases
Absorption
Distribution
Metabolism
Excretion
Onset
When the drug begins to work
Peak
Drug at highest blood level-most amount of drug available ot go to target tissues.
Duration
Length of time
ACE inhibitors
Angiotestin Converting Enzyme
Angiotensin II
vasioconstrictor
Toxicity
High concentration of drug in bloodstream
Tolerence
decreased responce to drug
Synergistic
Drugs interact to increase the effect of one or both drugs
Effects of drugs
Stimulate Body Functions
Depress Body Functions
Replace Body Functions
Destroy Cells
Agonist action
attach to a receptor
to cause a response
Antagonist action
Attach to a receptor
to block a response
Physical Dependance
need to continue to prevent
withdrawal
symptoms
Psychological Dependance
compulsive need to use substance
Addiction
disease process characterizied by continued use of a specific psychoactive substance
Author
Anonymous
ID
68259
Card Set
Pharmacology
Description
definitions
Updated
2011-02-23T01:53:42Z
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