Pharmacology

The study of what happens to a drug from the time it is put in to the body until the parent drugand all metabolites have left the body.

• Assessment
• Nursing Diagnosis
• Planning
• Implementation
• Evaluation

Taking all doses of medications correctly over prescribed length of therapy

Failure to follow directions

Lack of knowledge

an inactive (inert) substance

self medication

• the transferring of responsibility for the performance of an activity or taskwhile retaining accountability for the outcome.
• THE TASK IS DELEGATED NOT THE PATIENT

• Right Task
• Right Circumstance
• Right Person
• Right Directions/Communication
• Right Supervision

Drug enters blood stream

Drug circulates through body

Drug broken down into metabolites- usually in liver

Drug eliminated from body

time 1/2 drug eliminated from body - important for dosing time.

Age, weight, gender, dosage, route, food and drug interactions, genetics and race, pathologic conditions, psychological

Drug A & B (similuar effects) double effect

Drug A & B (Different actions) greater than effect of single drugs. More than doubled.

Drug A displaces Drug B from plasma protein binding sites- more free drug B- greater effect of drug B

Drug A interfers with excretion or metabolism of Drug B- Drug B in body longer- increase effect of Drug B

Molecules move with the concentration gradient (greater to lesser)until equilibrium is reached

Molecules move against the concentrated gradient

The study of what drug does to the body. How the drug works.

• Absorption
• Distribution
• Metabolism
• Excretion

When the drug begins to work

Drug at highest blood level-most amount of drug available ot go to target tissues.

Length of time

Angiotestin Converting Enzyme

vasioconstrictor

High concentration of drug in bloodstream

decreased responce to drug

Drugs interact to increase the effect of one or both drugs

• Stimulate Body Functions
• Depress Body Functions
• Replace Body Functions
• Destroy Cells

attach to a receptor to cause a response

Attach to a receptor to block a response

need to continue to prevent withdrawal symptoms

compulsive need to use substance

disease process characterizied by continued use of a specific psychoactive substance