neuro cancers

Most common adult primary brain tumor. Grave prognosis (<1 year life expectancy) Found in both hemispheres because it can cross the corpus callosum (like a butterfly-butterfly glioma). Stains positive for GFAP (astrocyte marker)

Second most common adult primary brain tumor. Often occurs in convexities of hemispheres and parasagittal region. Arises from arachnoid cells external to brain. Resectable.

Third most common adult primary brain tumor. Schwann cell origin-often localized to CN VIII. Resectable

Relatively rare, slow growing brain tumore. Most often in frontal lobes. Chicken wire capillary pattern

Most commonly prolactinoma. Bitemporal hemianopia (due to pressure on optic chiasm) and hyper/hypo-pituitarism are sequelae.

Usually well-circumscribed. In children most often found int the posterior fossa. May be supratentorial. GFAP positive. Benign, good prognosis

Highly malignant cerebellar tumor more common in children. A from of primative neuroectodermal tumor (PNET). Can compress 4th ventricle, causing hydrocephalus.

Ependymal cell tumors most commonly found in the 4th ventricle; can cause hydrocephalus. Poor prognosis. More common in children

Most often cerebellar and in kiddos; associated with von Hippel-Lindau syndrom when found with retinal angiomas. Can produce EPO causing polycythemia

Benign childhood tumor confused with pititary adenoma (can cause bilat hemianopia). Most common childhood supratentorial tumor.

Pseudopalisading pleomorphic tumor cells--border central areas of necrosis and hemorrhage

spindle cells concentrically arranged in a whorled pattern; psammoma bodies (laminated calcifications)

Bilat tumor found in neurofibromatosis type 2

"fried egg" cells-round nuclei with clear cytoplasm (halos) often calcified

Derived from Rathke's pouch

Rosenthal fibers--eosinophilic, corkscrew fibers

Rosettes or perivascular pseudorosette pattern of cells. Radiosensitive

Chracteristic perivascualr pseudorosettes. Rod-shaped blepharoplasts (basal ciliary bodies) found near nucleus.

foamy cells and high vascularity are characteristic

derived from remnants of rathke's pouch. Calcification is common (tooth enamel-like)