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Pharmacology

  1. sputum or (phlegm)
    an Abnormal viscous secretion that is a production of the lower respiratory tree; It consists mainly of mucus.
  2. mucus
    fluid secreted by mucus membranes and glands.

    95% water
  3. nebulizer
    • equipment for producing a fine spray or mist
    • by rapidly passing air through or vibrating a liquid

    to produce small particles
  4. mucolytics
    agents that have a disintegrating effect on mucus

    (Expectorant) and promotes coughing or spitting to help remove mucus
  5. mucokinetic agent
    an agent that helps move mucus along the trachebronchial tree
  6. aerosol therapy
    a form of inhaled, topical pulmonary treatment
  7. purulent
    forming or containing pus
  8. atelectasis
    a collapsed or airless condition of the lung
  9. bronchoconstriction
    narrowing of the bronchial tubes
  10. Xanthine bronchodilators
    chemicals that cause bronchodilation by inhibiting the enzyme phosphodiesterase

    increases the cyclic adenosine monophosphate level (CAMP)

    stimulates the medulla and CNS to....

    • -decrease airway reactivity
    • -relax bronchial smooth muscle
    • -stimulate breathing
  11. pathophysiology
    the study of how normal function and processes of the body are altered by disease
  12. agonist
    drugs that mimic the body's own regulatory function by...

    -binding to and stimulating receptors in the body
  13. antagonist
    counteracts the action of something else....

    -inhibits
  14. adrenergic

    sympathomimetic

    catecholamine
    • nerve fibers that release
    • -norepinephrine
    • -epinephrine

    in the CNS

    "FIGHT OR FLIGHT RESPONSE"
  15. acetylcholine (Ach)
    PNS neurotransmitter

    activated by the enzyme cholinesterase
  16. anticholinergic

    parasympatholytic

    cholinergic blocker
    blocking cholinergic or parasympathetic nerve fibers

    (Acetylcholine blocker)
  17. Leukotrienes
    a class of bilogically active compounds and mediator of inflammation

    found in the human airway that produce allergic and inflammatory reactions similar to those of histamine
  18. Leukotriene receptor inhibitors (Agonists)
    drugs that prevent leukotrienes from binding to receptor sites in the human airway
  19. salmeterol
    serevent

    • Beta2 agonist- long acting
  20. albuterol
    proventil

    Beta2 agonist- short acting
  21. ipratropium
    atrovent

    Anticholinergic
  22. methylprednisolone
    solu medrol

    systemic corticosteroid
  23. fluticasone propionate
    flonase, flovent

    inhalation corticosteroid
  24. montelukast
    singulair

    leukotriene inhibitor
  25. cromolyn
    intal

    mast cell stabilizor
  26. theophylline
    slobid

    xanthine
  27. which 2 drugs do you want to avoid with xanthine derivatives?
    erythromycin and Cipro

    **they decrease hepatic clearance of the drug and cause syrum levels to rise
  28. why does smoking interact with xanthine?
    smoking decreases the 1/2 life

    causing a need to increase the dose amount
  29. why can alupent be used with albuterol?
    alupent effects more Beta1 than Beta2 so that is why you can combine them

    albuterol activates CAMP; smooth muscle relaxes
  30. Isotonic Saline Solution
    0.9%

    hydration
  31. Hypotonic Saline Solution
    0.45%

    more distal airways
  32. Hypertonic Saline Solutions
    1.8%

    irritates throat; produces cough
  33. nonproductive cough
    dry barking
  34. congested and nonproductive cough
    sounds moist

    not expectorating mucus
  35. congested and productive cough
    • moist
    • can expectorate mucus
  36. what drug potentiates Beta-agonist drugs?
    corticosteroids
  37. Metaproterenol (Alupent)
    1 minute onset
  38. Albuterol (Proventil, Ventolin)
    5-15 min. onset
Author
aschecher
ID
68013
Card Set
Pharmacology
Description
Respiratory I
Updated

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