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sputum
or (phlegm)
an
Abnormal
viscous secretion that is a production of the lower respiratory tree; It consists mainly of mucus.
mucus
fluid secreted by mucus membranes and glands.
95% water
nebulizer
equipment for producing a fine spray or mist
by rapidly passing air through or vibrating a liquid
to produce small particles
mucolytics
agents that have a disintegrating effect on mucus
(
Expectorant)
and promotes coughing or spitting to help remove mucus
mucokinetic agent
an agent that helps move mucus along the trachebronchial tree
aerosol therapy
a form of
inhaled
, topical pulmonary treatment
purulent
forming or containing pus
atelectasis
a collapsed or airless condition of the lung
bronchoconstriction
narrowing of the bronchial tubes
Xanthine bronchodilators
chemicals that cause bronchodilation by inhibiting the enzyme phosphodiesterase
increases the cyclic adenosine monophosphate level (CAMP)
stimulates the medulla and CNS to....
-decrease airway reactivity
-relax bronchial smooth muscle
-stimulate breathing
pathophysiology
the study of how normal function and processes of the body are altered by disease
agonist
drugs that mimic the body's own regulatory function by...
-binding to and stimulating receptors in the body
antagonist
counteracts the action of something else....
-inhibits
adrenergic
sympathomimetic
catecholamine
nerve fibers that release
-norepinephrine
-epinephrine
in the CNS
"FIGHT OR FLIGHT RESPONSE"
acetylcholine (Ach)
PNS neurotransmitter
activated by the enzyme cholinesterase
anticholinergic
parasympatholytic
cholinergic blocker
blocking cholinergic or parasympathetic nerve fibers
(Acetylcholine blocker)
Leukotrienes
a class of bilogically active compounds and mediator of inflammation
found in the human airway that
produce
allergic and inflammatory reactions
similar to those of
histamine
Leukotriene receptor inhibitors (Agonists)
drugs that prevent leukotrienes from binding to receptor sites in the human airway
salmeterol
serevent
Beta
2
agonist- long acting
albuterol
proventil
Beta
2
agonist- short acting
ipratropium
atrovent
Anticholinergic
methylprednisolone
solu medrol
systemic corticosteroid
fluticasone propionate
flonase, flovent
inhalation corticosteroid
montelukast
singulair
leukotriene inhibitor
cromolyn
intal
mast cell stabilizor
theophylline
slobid
xanthine
which 2 drugs do you want to avoid with xanthine derivatives?
erythromycin and Cipro
**they decrease hepatic clearance of the drug and cause syrum levels to rise
why does smoking interact with xanthine?
smoking decreases the 1/2 life
causing a need to
increase
the dose amount
why can alupent be used with albuterol?
alupent effects more Beta
1
than Beta
2
so that is why you can combine them
albuterol activates CAMP; smooth muscle relaxes
Isotonic Saline Solution
0.9%
hydration
Hypotonic Saline Solution
0.45%
more distal airways
Hypertonic Saline Solutions
1.8%
irritates throat; produces cough
nonproductive cough
dry barking
congested and nonproductive cough
sounds moist
not expectorating mucus
congested and productive cough
moist
can expectorate mucus
what drug potentiates Beta-agonist drugs?
corticosteroids
Metaproterenol (Alupent)
1 minute onset
Albuterol (Proventil, Ventolin)
5-15 min. onset
Author
aschecher
ID
68013
Card Set
Pharmacology
Description
Respiratory I
Updated
2011-02-22T02:52:41Z
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