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Define Schizophrenia
A psychosis characterized by abnormalities in perception, context of thought, & thought processes, & extensive withdrawl of one's interest from people & the outside world
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Define Psychosis
- A sx
- A state in which the individual is experiencing hallucinations delusions or disorganized thoughts, speech or behavior
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Define Schizophrenia
- A mental illness which interferes with a person's ability to:
- Think clearly
- Manage emotions
- Make decisions
- Relate to others
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Discuss epidemiology in Schizophrenia
- Lower socioeconomic groups
- Homeless
- Majority 16-25
- Women have later onset than men
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What are positive symptoms?
- Things that are there but should not be there
- Hallucinations
- Delusions
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Define Hallucinations
Perceptual experiences that occur without actual external sensory stimuli. They can include all 5 senses.
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Define Delusions
- Erroneous fixed beliefs that cannot be changed by reasonable argument
- Grandiose
- Nihilistic
- Persecutory
- Somatic
- Religious
- Referential
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Define the delusion Grandiose
Belief that one has exceptional powers, wealth, skills, influence, destiny
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Define the delusion Nihilistic
Belief that one is dead or a disaster is impending
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Define the delusion Persecutory
Belief that one is being watched, plotted against, ridiculed...
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Define the delusion Somatic
- Belief about abnormalities in body fxn or structure
- ex. may have intense fear they are ugly
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Define the delusion Religious
Has a godly mission, or relationship with God
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Define the delusion Referential
Tv or radio is talking to them
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Discuss Thought Broadcasting and Thought Insertion
- Think people can read their minds
- Think people are putting thoughts into their head
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List Negative Symptoms
- Affective flattening or blunting
- Ambivalence
- Alogia
- Avolition
- Anhedonia
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Define negative sx Ambivalence
Presence of two opposing forces, leading to inaction (don't do anything), (inability to concentrate)
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Define negative sx Alogia
Brief and lack of content verbal responses (poverty of speech)
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Define negative sx Avolition
Inability to complete projects, assignments, or work
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Define negative sx Anhedonia
Inability to gain pleasure
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Define disorganized speech Echolalia
Repetition of another's words
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Define disorganized speech Circumstantiality
Extremely detailed & lengthy talk about a topic
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Define disorganized speech Loose Associations
Absence of normal connectedness of thoughts, ideas, & topics
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Define disorganized speech Tangentiality
Change in topic that is logical but detours from original topic
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Define disorganized speech Flight of Ideas
Topic of conversation changes repeatedly & rapidly
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Define disorganized speech Word Salad
String of words totally unconnected
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Define disorganized speech Neologisms
Made up words
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Define disorganized speech Paranoia
Suspiciousness that is unrealistic
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Define disorganized speech Referential Thinking
Belief that neutral stimuli have special meaning
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Define disorganized speech Autisitic Thinking
Restricts thinking to the literal & immediate makes no sense to anyone else
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Define disorganized speech Concrete Thinking
Lack of abstract thinking
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Define disorganized speech Verbigeration
Purposeless repetition of words/phrases
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Define disorganized speech Metonymic Speeech
Use of words interchangeably with similar meanings
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Define disorganized speech Clang Association
- Repetition of words that are similar in sound but in no other way
- ex. I am going to cry, lie, die
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Define disorganized speech Stilted Language
Overly & artificial formal language
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Define disorganized speech Pressured Speech
As if words are being forced out
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Define disorganized behavior Aggression
Behaviors or attitudes that reflect rage
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Define disorganized behavior Agitation
Inability to sit still or attend to others
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Define disorganized behavior Catatonic Excitement
- Hyperactivity characterized by purposeless activity & abnormal movements
- ex. excessively writing name, or pacing movements
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Define disorganized behavior Echopraxia
Involuntary imitation of another's movements & gestures
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Define disorganized behavior Regressed Behavior
Childlike/immature
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Define disorganized behavior Stereotype
Repetitive purposeless movements that are idiosyncratic to the person
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Define disorganized behavior Hypervigilance
- Sustained attention to external stimuli
- ex. fixed and waiting to something to happen (waiting for FBI to come out of woods)
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Define disorganized behavior Waxy Flexibility
Posture held in fixed position (if you moved their arm up, they would still be "frozen")
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List the 4 Stages of Schizophrenia
- Acute Illness Period
- Stabilization Period
- Maintenance & Recovery Period
- Relapse Period
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Discuss the Acute Illness Period of Schizophrenia
- Confusing and frightening behaviors
- Subtle progressing to disruptive & bizarre
- Pt is progressively unable to meet basic needs, work and everything deteriorates
- Substance use common
- Generally not violent, unless substance use or not taking meds
- Dependence on family/friends increases
- Cognitive deficits
- High risk for suicide
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Discuss the Stabilization Period of Schizophrenia
- Occurs after Dx and initial Tx
- Sx become less acute, but still present (give coping skills)
- Intense med Tx
- Treatable not curable
- Pt and family adjust to life-long/chronic dx reality
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Discuss the Maintenance & Recovery Period of Schizophrenia
- After stablized
- Focus on regaining previous level of fxn
- Meds improve, not cure
- Adherence with meds is vital
- Stress can exacerbate
- *Family support
- *Educate pt and family (NAMI)
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Discuss Relapse in Schizophrenia
- Occurs during Tx and Recovery
- Detremintal to mgt
- Each relapse- longer time to recovery
- Meds + therapy = less relapses
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List the 3 parts to tx Schizophrenia
- Medication
- Structured Activities/ Therapy
- Family Support
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List Typical Antipsychotics
- Thorazine
- Prolixin
- Mellaril
- Haldol
- Navane
- Stelazine
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List Typical Antipsychotics SE
- Anticholinergic
- Sedation
- EPS
- Hypotension
- Seizure
- Agranulocytosis
- NMS
- TD
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List Atypical Antipsychotics
- Clozaril
- Zyprexa
- Seroquel
- Respiradol
- Geodone (helps depression too)
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List Atypical Antipsychotics SE
- Weight Gain*
- Changes in metabolism including DM and hyperprolacteremia
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List Theories/ Predisposing Factors to Schizophrenia
- Biological: genetic (1 degree relatives), biochemical, physiological
- Psychological
- Environmental: stress (triggers gene)
- Dopamine
- **Still Don't Know
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Discuss Diagnostic Criteria for Schizophrenia (DSM IV)
- 2 or more of the following during 1 mo, persisting for at least 6 mo:
- delusions
- hallucinations
- disorganized speech
- disorganised or catatonic behavior
- negative sx
- Plus 1 or more major areas of social or occupational functioning below previous level
- And absence of major depression, manic, or mixed episodes with concurrent active sx
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Define Paranoid
- Any type of delusion
- Least functional impairment
- High suicide risk
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Define Catatonic
- Bizarre posture
- In illnesses other than Schizo
- ECT effective
- Need ROM, IVs, Shock Tx
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Define Disorganized Schizophrenia
- Inappropriate affect
- Most impaired
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Define Undifferentiated Schizophrenia
- Doesn't fit DSM IV
- Not sure what to call
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Define Schizoaffective D/O
- Schizo and mood d/o
- Diagnosis: Uninterrupted period manic or mixed major depression with 2 Schizo sx
- Long term better than schizo, but worse than MDD
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List parts of Mental Status Exam
- Content of thought
- Form of thought
- Perceptions
- Affect
- Sense of self
- Social Fxn
- Hygiene
- Psychomotor
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List Additional Assessment of Schizophrenia
- Family (genetic dx)
- Past
- Current Physical Health
- Level of anxiety
- SI/HI
- Labs (Lithium)
- Meds
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List common Nsg Dx for Schizophrenia
- Risk for Safety (#1)
- Disturbed Thought or Sensory
- Social Isolation
- Impaired Verbal
- Self-Care Deficit
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List common Pt Outcomes for Schizophrenia
- Demonstrates an ability to relate satisfactorily
- Recognizes distorted thinking
- No harm to self or others
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List common Nsg Interventions for Schizophrenia
- Initiate safety measure for suicide/ aggression
- Intervening with delusions, hallucinations, paranoia
- Reality testing
- Improving social isolation
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List working w/ pts w/ Delusions & Hallucinations
- Do not feed into delusions
- Safe environment
- Dec stimulation
- Simple statements
- Recognize their reality
- Use distraction
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Discuss NMS
- Rare but Fatal
- Severe muscle rigidity, elevated temp (up to 107)
- Sx: elevated temp, change in LOC, leukocytosis, elevated creatine, elevated liver enzymes
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List Nsg Intervention/ Tx for NMS
- Stop administration of offending med
- Monitor VS
- Reduce body temp
- Safety, protect muscle
- Supportive measures
- IV fluids
- Cardiac monitoring
- Admin Dopamine agonist
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Discuss Anticholinergic Crisis
- Potentially life-threatening
- Occurs in pt w/ several meds w/ anticholinergic effects
- Sx: elevated temp, dry mouth, dec salivation, dec bronchial, nasal secretion, widely dilated eyes
- Confusion, hallucinations
- Self-limiting (3 days)
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List Nsg Intervention/ Tx for Anticholinergic Crisis
- D/c med
- Physiostigmine 1-2mg IV
- Gastic lavage
- Charcoal, catharsis
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Discuss EPS
- Pseudoparkinsonism: muscle rigidity & absence of movement
- Dystonia: muscles tense and body contorts
- Oculogyric crisis: eye muscles tighten and eyes roll back
- Akathisia: restless, need to keep moving
- Akinesia: absence or loss of voluntary movement
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List Nsg Intervention/ Tx for EPS
- Benzotropine (Cogentin)
- Trihexphenidyl (Artane)
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Discuss TD
- Major risk for pts on long-term neuroleptic meds
- Bizarre movements: lip smacking, tongue movements, difficulty swallowing, pill rolling, & gestures
- Tx: D/C meds at onset tongue movements
- May be irreversible
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Discuss Agranulocytosis
- Dec ability to fight off infection
- Esp. w/ Clozaril
- Monitor WBC weekly first 6 mo
- Reversible if tx early
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Discuss Metabolic Syndrome
- Results in: DM/ Hyperglycemia
- Monitor wt and girth
- Initial Glucose tolerance test
- Monitor blood glucose
- Provide nutrition & activity support
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Discuss Client/ Family Education: Nature of the Illness
- What to expect as illness progresses
- Sx associated w/ illness
- Ways for family to respond to behaviors associated w/ illness
- Outside support
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Discuss Client/ Family Education: Mgt of Illness
- Connect exacerbation of sx to stress
- Med mgt (guardian)
- Social skills training
- Daily living skills training
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Discuss Client/ Family Education: Support Services
- Financial assistance
- Legal assistance (guardian)
- Caregiver support group
- Respite care
- Home Health
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State Time Period of Brief Psychotic Episode
Length 1 day, less than 1 mo
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Define Schizophreniform D/O
Pt has schizo for less than 6 mo
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Discuss Delusional D/O
- Psychotic d/o (nonbizarre, stable)
- Delusions w/o mental d/o
- Delusions could be real life (followed, poisoned)
- Somatic delusions- bring to hospital
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Discuss Shared Psychotic D/O (folie'adeux)
- Psychosis transmitted to another person (in close proximity)
- When tx psychotic person, other pt resolved
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List Common Misconceptions about Schizophrenia
- Not split personality
- Not caused by dysfxn families
- Not caused by poverty (but leads to)
- Not more violent
- IS HOPE
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