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MM19
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If a death signal comes from inside, this enzyme is activated
Caspase 9
This is released by mitochondrion in apoptosis
cytochrome c
How does internal apoptosis happen?
Cyt
C
-
Apaf
1
complex
caspase 9
What are the ingredients of an apoptosome?
Cyt C
Apaf-1
Caspase 9
This prevents release of Cyt C
Bcl2
How does external apoptosis happen?
Fas-Fas
Trimerization
FADD
Caspase 8
A receptor which binds a death ligand but doesn’t work
decoy receptor
too much of it in tumors
This stuff promotes mitosis
growth factors
EGF
This stuff inhibits mitosis by blocking activation of Rb
TGF-B
What does an APC do?
Makes sure spindle fibers is attached to centromeres
Author
Bobopudge
ID
67425
Card Set
MM19
Description
Cell death
Updated
2011-02-19T14:51:53Z
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