MM19

If a death signal comes from inside, this enzyme is activated

Caspase 9
This is released by mitochondrion in apoptosis

cytochrome c
How does internal apoptosis happen?
- CytC-Apaf1 complex
- caspase 9
What are the ingredients of an apoptosome?
- Cyt C
- Apaf-1
- Caspase 9
This prevents release of Cyt C

Bcl2
How does external apoptosis happen?
- Fas-Fas
- Trimerization
- FADD
- Caspase 8
A receptor which binds a death ligand but doesn’t work
- decoy receptor
- too much of it in tumors
This stuff promotes mitosis
- growth factors
- EGF
This stuff inhibits mitosis by blocking activation of Rb

TGF-B
What does an APC do?

Makes sure spindle fibers is attached to centromeres

Author

Bobopudge

67425

Card Set

MM19

Description

Cell death

Updated

2011-02-19T14:51:53Z