Discuss the assessment, treatment, and follow up of a patient with a positive PPD using evidence-based protocols and guidelines.
- The CDC's recommendations found in Morbidity and Mortality Weekly Report (MMWR)
- The management of TB depends on the classification of the disease based on the pathogenesis and diagnostic results.
- Class 0 and 1 no tx. Class 1 should have a repeat test several months after exposure.
Class 2 Main purpose of preventive therapy is decrease the risk that LTBI will progress to active TB. Isoniazid (INH) 300mg/day 6-12 months.
Class 3 requires multidrug therapy. Initial tx regimen: isoniazid, rifampin, pyrazinamide (PZA) and ethambutol is used to prevent MDR TB. Once drug susceptibility to isoniazid and rifampin is demonstrated, administration of these two drugs is continued after the initital 2 months of multidrug therapy.
Monthly follow up evals at the least