-
actin and myosin
helps heal wounds
do not need fibrin mesh anymore
platelets
-
to break apart fibrin
plasmin breaks up fibrin mesh
*cut is now healed
fibrinolysis
-
form clots when there is no injury
thromboembolitic disorders
-
cannot form clots at all, males only
hemophelia
-
anemia > hematocrite
glucose > diabetes
lipids > cholesterol
leukocytes > WBC's
different types of blood tests
-
the heart is a ________ pump
double
-
location of heart
mediastinum
-
2 layers, outermost (lining of heart)
- fibrous layer
- fluid
- serous layer
-
cardiac muscle, controlled by nervous system, contraction/signaling (sympathetic nervous system) (lining of heart)
myocardium
-
innermost layer of heart
endocardium
-
right coronary
right marginal
posterior interventricular
left coronary > circumflex, anterior interventricular
arteries
-
small
middle
great
-all go to coronary sinus
-coronary sinus then returns blood to right atrium
cardiac veins
-
superior vena cava, inferior vena cava, and coronary sinus brings blood to ________
atrium
-
temporary lack of oxygen, heart will hurt
angina pectoris
-
heart attack
carinary
myocardial infarction
-
vasospasm
sympathetic (autonomic)
-
when ventricle contracts, AV valve closed
systole
-
when ventricle relaxes, AV valve opened, filling with blood
diastole
-
differences in prssure on each side determines when AV valve is ________/________
open/closed
-
________ ________/papillary muscle controls opening and closing of valve
chordae tendinae
-
sound heart makes when AV valve is closing
lub
-
sound heart makes when AV valve is opening
dup
-
any other sound the heart makes (besides lub-dup-pause) is a ________
murmur
-
when valve cannot open all the way
stenosis
-
when valve cannot close all the way
incompetant
-
second major control system
hormones > chemical messages
acts very slow
endocrine system
-
permeability and membrane potential can be changed by ________ or synthesize of protein or increases cytosis
hormones
-
-one hormone cannot be effective without another
ex) reproductive hormones cannot be efficient without thyroid hormones > puberty
permissiveness
-
one and one will equal more than two
ex) glucagen will increase blood glucose levels
epinephrine ^
^-50, ^-50, = 150
synergism
-
opposite of synergism, glucagen increases/insulin decreases
antagonism
-
humoral stimuli > ion or nutrients
*neural stimuli > epinephrine
hormonal stimuli > tells other hormones to start doing their job
hormone release
-
turning on another system > trophic, tropic
1. growth hormone > bones and ligaments will grow
2. thyroid stimulating hormone (TSH) released
3. adrenocorticotropic hormone (ACTH)
4. Gonadotropic
pituitary gland
-
-
follicle stimulating hormone
follicle wrapping
-
secondary sexual characteristics
>boobies, wider hips, hair, menstrual cycle, menarche
estrogen
-
inner linger of uterus for baby, cranky moods
progesterone
-
testes
1. sperm
2. testosterone > secondary characteristics of males (androgens)
-deep voice
-bigger/stronger muscles
-hair everywhere
anterior pituitary gland
-
produces milk for women
prolactin
-
oxytocin helps push baby out
anti-diuretic H (ADH) > keep fluid in
^^opposite alcohol
posterior pituitary gland
-
basal metabolic rate
controls body heat
maintains blood pressure
cannot go through/growth reproduction w/o it
thyroid gland
-
controls metabolism (hormone)
thyroxine
-
very important ion
*will reduce blood Ca++ levels, goes to bones
calcitonin hormone
-
increases Ca++ levels/(antagonist) to calcitonin
most important hormone
parathyroid hormone
-
helps thyroid gland
in salt
iodine
-
secretes (24) hormones
cortex
-
supra renal glands
two groups: 1) mineral corticoids > controls electrolytes (salts) in the extracellular fluid
2) gluco corticoids > sugar metabolism, maintaing proper blood pressure
adrenal glands
-
sympathetic system is needed and epinephrine
catecholamines
-
long term ________ will:
1. retain sodium > high BP
2. muscle tissue will be converted to muscles
3. diabetes, suppression to immune system
stress
-
-mainly exocrine
-secretes enzymes in digestion
-made of exocrine tissue
-the islets secrete
hormones: glucagon, raises blood sugar level
insulin, lowers blood sugar level
pancreas
-
adipose tissue > leptin
stomach > gastrin (response to food)
duoderum > peptide (response to food)
kidney > erythroprotein (produce RBCs)
skin > cholocalciferol (vitamin D)
tissues that secrete hormones
-
vein is place to get blood, deoxyginated
blood
-
1. transportation/distribution of blood
2. regulation
a) body temp
b) pH level
c) fluid volume (BP)
3. protection
a) blood clotting
b) pathogens
functions of blood
-
vitamins A, D, E, K are all ________ ________
fat soluble
-
carry oxygen
hemoglobin and spectrin
erythrocytes (RBCs)
-
protein that carries iron, lungs will carry oxygen all over body
hemoglobin
-
protein that is in RBCs to change shape to fit in capillaries
spectrin
-
bright red, oxygen present
oxyhemoglobin
-
no oxygen present
deoxyhemoglobin
-
hemoglobin and CO2
carbaminoglobin
-
to make new RBCs
bone marrow
erythropolesis
-
stage of development right before RBC matures
nucleus is protected leaving no nucleus
reticulocyte
-
includes all events associated with blood flow through the heart during one complete beat
cardiac cycle
-
pressure shoots up a little bit when aortic semi-lunar valve closes
diocrotic notch
-
volume of blood pumped out by one ventricle with each beat
stroke volume
-
how many times your heart beats per minute
heart rate
-
-stroke volume x heart rate
-amount of blood pumped out by each ventricle in one minute
cardiac output
-
speeds heart up
sympathetic
-
slows heart down
parasympathetic
-
hormone (epinephrine) changes heart rate, adrenal glands
-hypo > slower (thyroid)
endocrine influence
-
too much increases heart rate
not enough decreases heart rate
(ion)
calcium ion
-
resting pulse is greater than 100
too fast
tachycardia
-
resting pulse is below 50-60
too slow
not enough oxygen
bradycardia
-
causes: valve problems, intrinsic conduction problems
congestive heart failure
-
space where blood goes through
lumen
-
takes blood away from heart
small lumen
big tunica media
artery
-
takes blood towards heart
larger lumen
smaller tunica media
vein
-
biggest arteries
-aorta
-expand during systole
-contract during diastole
-thick walls
-pressure reservoirs, try to even out dramatic push
elastic arteries
-
can go through vasodilation and vasoconstriction
muscular vessels
-
smallest arteries
aterioles
-
exchanges take place
very small vessels
3 different types
capillaries
-
least permeable
most common
ex) skin, muscle
(capillary)
continuous
-
large fenestrations (pores)
increased permeability
occurs in special places
ex) kidney, small intestine
(capillary)
fenestrated
-
most permeable
ex: liver, bone marrow, spleen
(capillary)
sinusoidal
-
body condition, if just sitting down don't need as much blood/O2 as if you were running around
capillary beds
-
capacitance
blood reservoirs
little veins = venules, smallest
skeletal muscle pump & respiratory pump > help to return blood
veins
-
causes > pregnancy, genetics, lousy muscle tone
once you have them, you cannot get rid of them
varicose veins
-
force per unit area exerted on a vessel wall
blood pressure
-
type of mechano receptor, measures pressure of blood, lets nervous system know what is going on (stand up too quick, feel light-headed > these tell the body that we need more blood flow to head)
baroreceptors
-
high to low
the bigger the difference, the faster the blood flow
pressure gradient
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