Physical Delivery Methods
Designed to dissolve slowly between the cheek and the gum; bypasses GI tract and allows for prolonged medication release.
AKA SL tablets. Dissolve quickly under the tongue for nearly immediate effects.
Dissolves in water or other solution.
Used for those with difficulty swallowing normal tablets; usually children and the elderly.
Designed to delay release until it reaches the intestine.
Reasons to use Enteric Coated tablets:
1. Drug is ineffective if it is absorbed in the stomach
2. Drug is Harmful to the stomach.
Film Coated Tablet
Covered with a layer of film; used to mask drug taste
2nd most common; Enclosed in hard or soft gelatin
Hard gelatin coating on a capsule contains?
powder or granules
Soft gelatin coating contains?
outdated; made from powdered plant or animal components; rolled with active ingredient and adhesive to make solid.
Dissolve in mouth; look like hard candy
Hard or gummy; same as lozenge
Can be taken externally by applying to the skin or internally by mixing with a drink
Designed to be inserted into a body cavity other than the mouth, including urethra, rectum, or vagina. Melt at body temperature for delivery.
Suppositories just for the vagina.
What is the advantage to a liquid dosage form?
It is very easy to swallow
What are the shortcomings of liquid dosage forms?
Short shelf life, often require refrigeration, and may need something to mask the taste
Solvent completely dissolves in solution
Solutions that contain syrups
Solutions containing alcohol
Require addition of water by the pharmacy; deteriorates rapidly in liquid form; must be shaken before use. Labels necessary
Mix of oil and water with emulsifying agents. Must be shaken because they will separate over time.
Combination of sugar and alcohol intended for oral use.
Substances that evaporate quickly and require airtight containers
Uses a gas in a liquid
Can deliver medication
Liquids that dry to form a flexible film that can be removed. Ex. New Skin
Medicationt that is swished, but not swallowed
Directly injected; preparation requires aseptic technique
Solutions meant to be put in a nebulizer for delivery
applied to skin or mucous membrane; thick and greasy
Easy to wash off and leaves skin dry
Used for large or hairy areas
Semisolid; rubbed on skin; texture of jelly
Solidifies to become impermeable to water
Medication is absorbed through the skin from the tape and the skin is protected by the tape.
Have a reservoir of medication and release over time
Absorbed through the lungs; has very small particles
Object placed under the skin that delivers medication.
Medication is in gum and releases while chewed.
Solution sprayed up nose for either topical or systemic effect
Administers small, accurate dose to the eye or ear;eye must be prepared aseptically. Eye drops can be used in the ear.
Physical Delivery Methods
Listed in Pass Assured