Gene Mapping

What are syntenic genes?

genes on the same chromsome
What does theta measure?

frequency of recombination
What does it mean when theta is
0
0.5
- 0--loci too close for recombination
- 0.5-- recombination occurs, no linkage
When theta is 0.5 what is the ratio of recombinant to non-recombinant chromosomes?

1:1
What does it mean :
When alleles are said to be in coupling?
When alleles are said to be in repulsion?
- Coupling--cis-- on the same chromosomes
- Repulsion--trans--on different chromosomes
A set of alleles in coupling at a neighboring loci are called what?

Haplotype
What is done to measure large distances?

measure distances between many close markers and add them together
Does theta underestimate or overestimate the true genetic distance?

underestimates
What is the relative risk ratio?

expresses the extent to which an allele increases the risk of disease
What causes the length of a genetic map to be longer in females than in males?

more recombination points in females
Mapping the location of a disease gene by linkage analysis followed by attempts to identify the gene based on its map position is called?

Positional cloning
Interstitial deletion?

deletion not involving the terminal part of the chromosome
Elevated beta hcG, snowstorm appearance on sonogram?
- duplication of male chromosomes
- hydatidifrom mole
Stratification

marrying within a community

Author

pszurnicki

66060

Card Set

Gene Mapping

Description

Gene Mapping

Updated

2011-02-13T22:14:32Z

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