HMP shunt

Chronic granulomatosis result from what?

NADPH oxidase
What is the rate limiting step of HMP shunt?

G6PD
Which part of the HMP shunt is irriversible, the oxidative or nonoxidative part?

Oxidative
What is the purpose of HMP shunt?
- NADPH
- Ribose 5 phosphate
What hormone stimulates the HMP shunt?

Insulin
Transketolase uses what coenzyme?

Thiamine--Vit B1
Why would you see a deficient Pyruvate dehydrogenase complex in alcoholics?

Deficiency in Vit B1---thiamine...a cofactor for Pyruvate dehydrogenase complex
Whats the key enzyme is the nonoxidative part of HMP shunt?

Transketolase
G6PD deficiency results in what?

Hemolytic anemia
NADPH is used for what 3 purposes?
- Regenerate glutathione
- -cyt 450
- Oxidative Burst
- Nitric Oxide synthesis
A deficiency of transketolase would cause an accumulation of what product?

Ribose 5- Phosphate
What does a branching enzyme do?

Glycosyl alpha 1,4: alpha 1,6 Transferase

Author

pszurnicki

65782

Card Set

HMP shunt

Description

HMP shunt

Updated

2011-02-12T03:13:07Z

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