Perio exam I ch. 4

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The inflammatory response is influenced by what?

The immune response of the individule
host defense cells
- lymphocytes
- PMN's (neutrophils, WBCs)
- macrophages
3 models of disease activity
- continuous model theory
- random burst theory
- asynchronous multiple burst theory
continuous model theory
- slow and constant
- tooth loss and disease increase with age
random burst theory
- short bursts of disease and remission
- lose attachment at burst stages
- site specific and episodic
Oral defense mechanism (3)
- supragingival environment
- gingival crevice
- gingival connective tissue
asynchronous multiple burst theory
- disease correlated to limited time
- remission follows
first line of defense

PMN (neutrophil)
how long to PMNs live

5 days
how long to macrophages live

months
macrophages realease what two things
- prostaglandans
- cytokines
What are cytokines
- proteins
- reglate the activities of other cells
- cause the release of IL1 and TNF
Antibodies or complement that
bind to surface of bacteria

opsonins
activated when antibodies (proteins) bind to antigens (bacteria)

classic pathway
activated by endotoxins

alternative pathway
3ed pathway

specific proteins bound to proteins or carbs on bacteria
two types of immune response
- humoral
- cellular
What patrols the host

lymphocytes
three types of lymphocytes
- B cells
- T cells
- natural killer cells
activated when inflammatory resonse is inadequate

humoral response
B lymphocytes are transformed into
- plasma cells
- memory cells
Plasma cells make antibodies which bind to the antigen... what antibodies does it make

Immunoglobulins
B cells are found in the lamina propria at sites with periodontitis in how many cases

90%
What is cellular immunity good for

protection against viruses like HIV, fungi, cancer
what are the two types of t cells?
- helper t (CD4)
- suppressor (CD8)
Which t cell are AIDs patients missing?

helper T (CD4)
Which cells activate B cells?

helper T cells

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darbydo88

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Perio exam I ch. 4

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perio exam I

Updated

2011-02-09T04:15:25Z

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