Primary risk factor for perio disease
Protects the bacteria from external sources
such as antibiotics/antimicrobials
# of baceria in biofilm
< 10% pathogenic
# normal oral microbiota
>90% normal oral microbiota
When do u get aquired pellical?
first few hrs
4 things in aquired pellical
- crevicular fluid
After aquired pellical?
What does bacteria adhere to?
Prevotella intermedia causes?
Bacteria that recognized carb structure are called?
Bacteria in the red group?
- Tf (Bf)
- Td (T. denticola)
Aa is in which color?
Which color groups are the first colonizers?
Types of subg bacterial biofilms
- Tooth associated (attached)
- Tissue associated
Nutrients for subg biofilm
GCF contains Hemin-containing compounds that enhance the growth of porphymonas and prevotella sp.
GCF has a good property
Antimicrobial- prevents bacterimia and infections
What holds biofilm together and protects the bacteria?
Direct Effect of Bacterial Action
- Cytotoxic Agents (LPS/LOS, leucotoxins, lipoteichoic acid)
- Enzymes (MMPs)
Indirect Effect of Bacterial Action
- Immunopatholgic Mechanisms (antigens stimulate immune response)
- Combined mechanisms
Gram-negative bacterial cell wall
Released when bacteria die and lysis
Initiates inflammation and bone destruction
Found loosely attached to root cementum
Components of dental plaque biofilm
- Extracellular matrix
- Cells: WBC, RBC, epithelial, ghost cells
Extracellular matrix is what % of plaque
3 groups of factors
- local factors (environment)
- systemic factors (medical conditions)
- host factors (one's own body)
future health problems assc. with perio disease
- diabetes mellitus
- heart disease
General term for something released by bacteria