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Organs made of different tissues
Bones
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Types of tissue in bones
- 1. Osseous tissue
- 2. Connective tissue
- - Cartilage
- - Adipose
- - Dense CT
- 3. Epithelial tissue
- 4. Nervous tissue
- - NAV- nerve, artery, vein (How they travel)
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6 functions of bone
- 1. Support
- 2. Protection
- 3. Movement
- 4. Mineral Storage
- 5. Homopoiesis
- 6. Fat Storage
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Bone supports ______.
Posture
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Bone protects ______.
Internal organs
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Bone functions in movement as an _______.
attachment site for muscles, which allow us to move
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Bone functions as a mineral storage for what mineral?
Calcium
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Bone functions as homopoiesis by the _______.
Production of red blood cells that takes place in the bone marrow
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Bone functions as fat storage because it providese a _______.
Supply of energy
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What are the 5 types of bones?
- 1. Long Bone
- 2. Short Bone
- 3. Flat Bone
- 4. Irregular Bone
- 5. Sesamoid Bone
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-Type of bone that includes the humerus and femur
-Longer than they are wide and contain more compact bone than spongy bone
Long bone
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-Type of bone that includes the trapezoid
-Wider than they are long and contain more spongy bone than compact bone
Short bone
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-Type of bone that includes the sternum and skull
-Layer of spongy bone in between two layers of compact bone- diploe
Flat bone
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Type of bone that includes the vertebra
Irregular bone
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-Type of bone that includes the patella
-Usually always associated with attachment of tendons and ligaments
-Find them where there is a lot of friction
Sesamoid bone
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-Body of a long bone
-Also called shaft of the bone
Diaphysis
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-Proximal and distal
-Ends of the long bone
Epiphysis
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-Contains the growth plate (epiphysial plate/line)
-Located between the epiphysis and the Diaphysis
Metaphysis
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-Colored in blue, found at the ends of long bones
-Reduces friction between articulating bones
Articular Cartilage
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-Thin covering on the outside of the bone, tough
-2 layers
1. Fibrous dense irregular connective tissue layer
2. Osteogenic layer
Periosteum
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-Layer that gives nourishment to the bone
-When you break a bone, this is the part that will remodel the bone and help it to grow back
Osteogenic layer
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What are the two layers of the Periosteum?
- 1. Fibrous dense irregular connective tissue layer
- 2. Osteogenic layer
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-Lining of the medullary cavity
Endosteum
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-Hollow part of the bone in the diaphysis
-Bone marrow is found here
Medullary cavity
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Name 5 depressions or openings on bone surfaces
- 1. Fissure
- 2. Foramen
- 3. Fossa
- 4. Sulcus
- 5. Meatus
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Narrow slit between adjacent bones
Fissure
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Opening through which blood vessels and nerves pass
Foramen
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Indention or a shallow depression(muscle attachment)
Fossa
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Groove or a furrow
Sulcus
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Canal or a passageway
Meatus
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Name 3 processes that form joints
- 1. Condyle
- 2. Facet
- 3. Head
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Protuberance at the end of a bone
Condyle
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Found on the vertebra, smooth, flat articular surface
Facet
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Runded large part at the end of a long bone (proximal end)
Head
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Name the 7 processes that form attachment points for connective tissues
- 1. Crest
- 2. Epicondyle
- 3. Line
- 4. Spinous processes
- 5. Trochanter
- 6. Tubercle
- 7. Tuberosity
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Sits on top of a condyle
Epicondyle
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Line of demarcation, narrow slit or furrow, doesn’t indent very much, border
Line
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Slender projection
Spinous processes
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Very large projection
Trochanter
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Nodule or a small eminence
Tubercle
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Roughened part of the bone
Tuberosity
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Name the 4 bone tissue cell types
- 1. Osteogenic cell
- 2. Osteoblasts
- 3. Osteocytes
- 4. Osteoclasts
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-Bone tissue cell
-Can still divide
-Immature cell
-Undifferentiated
-Found in the Periosteum and endosteum
Osteogenic cell
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-Bone tissue cell
-Forms the bone matrix and collagen fibers
-Cannot divide
Osteoblasts
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-Bone tissue cell
-Maintains the health of the bone
-Maintenance
Osteocytes
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-Bone tissue cell
-Resorption- removes the old bone and breaks down the matrix so the process can start over again
-One big macrophage
Osteoclasts
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Describe the histology of compact bone
Contains:
- 1. Central Canal
- 2. Osteon
- 3. Lacunae
- 4. Caniliculi
- 5. Osteoytes
- 6. Intersitial lamella
- 7. Circumferential lamellae
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-Found in compact bone
-Perforating canal, brings blood vessels to the central canal
Central Canal
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-Found in compact bone
-Main organizing structure
-Contains concentric lamellae, lacunae, and osteocytes
Osteon
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-Found in compact bone
-Where osteocytes are found
Lacunae
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-Found in compact bone
-Fluid filled channels that help cells talk to each other
Caniliculi
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-Found in compact bone
-Older lamella that have been pushed out
Interstitial lamella
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-Found in compact bone
-Oldest lamella and start to wear away
Circumferential lamellae
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Describe the histology of spongy bone
Contains:
1. Trabeculae
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-Structure of spongy bone
-Contain osteoclasts, osteoblasts, and osteocytes
Trabeculae
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Compact and Spongy bone are distinguished from the other by differences in _____, ______, and ______.
location, density, and anatomy
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Describe the 4 main differences between compact and spongy bone
- 1. S: thinner C: thicker
- 2. S: less dense C: more dense
- 3. S: found on the interior of the bone C: found on the exterior of the bone
- 4. S: trabeculae C: osteons
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Name the 4 arteries that provide the blood supply of a long bone
- 1. Periosteal arteries
- 2. Nutrient arteries
- 3. Metaphyseal arteries
- 4. Epiphysial arteries
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-Delivers the blood to the periosteum
Periosteal arteries
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-This artery goes through the nutrient foremen
-Supply the medullary cavity
-Goes to the proximal and distal ends of the bone as well
Nutrient arteries
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-Arteries that go to the metaphysis and the epiphysis
Metaphyseal and epiphysial arteries
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Name the 4 veins that drain blood from bone
- 1. Periosteal veins
- 2. Nutrient veins
- 3. Metaphyseal veins
- 4. Epiphysial veins
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Drains blood from the periosteum
Periosteal veins
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Vein that goes through the nutrient foremen
Nutrient veins
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Drains blood from metaphysis and epiphysis
Metaphyseal/epiphysial veins
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Describe the steps of bone formation in Intermembranous Ossification (flat bones)
- 1. Development of the ossification center
- a. No mature cells yet
- 2. Calcification
- a. Mature cells, osteocytes in the lacunae
3. Formation of Trabeculae
- 4. Development of the periosteum
- a. Spongy bone between two layers of bone tissue
-Simpler process than endochondral ossification
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Decribe the steps of bone formation in Endochondral Ossification (most of the bones in the body)
1. Development of cartilage model
2. Growth of cartilage model
- 3. Development of primary ossification center
- a. Nutrient artery perforates the diaphysis of the bone
- b. Development of spongy bone
- 4. Development of the medullary cavity
- a. Maturing, takes shape of a regular bone
- 5. Development of secondary ossification center
- a. Secondary ossification at the epiphysis
6. Formation of articular cartilage and epiphysial plate
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In Endochondral Ossification, cartilage is replaced by ______; occurs for most bones of the body.
Bone
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Endochondral Ossification involves a ____ step process.
6
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The cartilage model of Endochondral Ossification grow in _____ by mitosis and by the deposition of _______.
Length; extracellular matrix
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"Growth in length" by the cartilage model
Interstitial fluid
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Growth of cartilage in thickness is due mainly to the addition of more extracellular matrix to the _______.
Periphery
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"Growth in thickness" of cartilage
Appositional growth
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Describe the steps of increases bone thickness via appositional growth
1. Ridges in periosteum create groove for Periosteal blood vessel
2. Periosteal ridges fuse, forming an endosteum-lined tunnel
3. Osteoblasts in endosteum build new concentric lamellae inward toward center of tunnel, forming a new Osteon
4. Bone grows outward as osteoblasts in periosteum build new circumferential lamellae. Osteon formation repeats as new Periosteal ridges fold over blood vessels
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The growth in length of a long bone involves:
- 1. Interstitial growth
- 2. (Role of epiphysial plate) Replacement of cartilage with bone by endochondral ossification on the diaphyseal side of the epiphysial plate
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Name the four layers of the epiphyseal that plate permits growth of long bones
- 1. Zone of resting cartilage
- 2. Zone of proliferating cartilage
- 3. Zone of hypertrophic cartilage
- 4. Zone of calcified cartilage
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Layer of Epiphysial Plate that anchors the growth plate to the bone
Zone of resting cartilage
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Layer of Epiphysial Plate that contains rapidly dividing cells
Zone of proliferating cartilage
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Layer of Epiphysial Plate in which cells enlarge a little but remain in stacks or columns
Zone of hypertrophic cartilage
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Layer of Epiphysial Plate that contains a thin zone of dead cells
Zone of calcified cartilage
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What are two ways bone can be remodeled
- 1. Done by Resorption (Taking the old matrix)
- 2. Bone deposition (New matrix is created)
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Literally means “porous bones”
Osteoporosis
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The problem with osteoporosis is that bone _____ outpaces bone ______.
Resorption (destruction); deposition (formation)
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Older women suffer from osteoporosis more often than men for two reasons:
- 1. Women contain estrogen
- 2. Production of the main androgen (testosterone)in older men wanes gradually and only slightly
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List the 7 types of bone fractures:
- 1. Open fracture
- 2. Comminuted fracture
- 3. Greenstick fracture
- 4. Impacted fracture
- 5. Pott's fracture
- 6. Colle's fracture
- 7. Stress fracture
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-Type of bone fracture
-Bone protrudes through the skin
-Dr. Hargroder playing soccer
Open fracture
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-Type of bone fracture
-Break pushes bone fragments in between the break
-Splinters and fragments lie near the break
Comminuted fracture
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-Type of bone fracture
-Only in children
-Break of one bone and bending of the other
Greenstick fracture
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-Type of bone fracture
-Jams bone or into bone socket
-Forcefully driven into the interior of the other bone
Impacted fracture
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-Type of bone fracture
-Common in soccer, in the leg
-Break in the lateral bone and problems with the distal articulation
Pott’s Fracture
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-Type of bone fracture
-In the arm, break in the lateral bone and articulation problems
Colles’ Fracture
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-Type of bone fracture
-Most common
-Microscopic fissures or fractures in bone that usually form from repeated, strenuous activites
-About 25% of these fractures involve the tibia
Stress Fracture
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