Immunology T1Ch2

  1. Organs are grouped into 2 main groups:
    Primary and secondary lymphoid organs
  2. primary lymphoid organs include:
    bone marrow and thymus
  3. secondary lymphoid organs include:
    spleen and lymph nodes
  4. There are tertiary lymphoid organs:
    GALT, BALT, genitourinary system

    **only have effector and memory cells**
  5. hematopoiesis
    formation and development of red and white blood cells
  6. all blood cells arise form
    hematopoietic stem cells (HSC)
  7. Why are HSCs difficult to study? (2 reasons)
    • 1. they are not abundant (1 in 50K cells)
    • 2. difficult to grow in vitro
  8. Hematopoiesis occurs at various sites throughout life.
    Where does is occur the first week of development?
    where does production decrease after adult stage?
    • yolk sac
    • liver and spleen
    • cranium, pelvis, sternum, ribs, vertebra, long bones
    • long bones
  9. where are HSCs located?
    bone marrow
  10. pluripotent/multipotent
    from one cell, other types of cells can be formed.
  11. unipotent
    can make only one kind of cell
  12. HSCs differentiate into:
    • Lymphoid progenitor cells LPC
    • Myeloid progenitor cells MPCs
Card Set
Immunology T1Ch2
test 1 chapter 2