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Antiviral for Influenza (1)
Oseltamivir - Tamiflu
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MOA for flu antivirals
Prevents infected host cell from releasing new virus
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Flu antiviral counseling points
- Side Effects: GI discomfort, take with food to reduce
- Contraindicated with live vaccine (2 weeks pre, 2 days post)
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Herpes Antivirals (3)
- Acyclovir - Zovirax
- Valacyclovir - Valtrex
- Famciclovir - Famvir
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Herpes antiviral MOA
interferes with viral DNA replication by terminating DNA chain
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Herpes antiviral indications
- Herpes Labalis - acyclovir, valacyclovir, famciclovir
- Genital Herpes - all
- Herpes Zoster - all
- Varicella-Zoster - acyclovir, valacyclovir
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Herpes antiviral counseling points
- Side Effects: N/V/D
- Doesn't really cure anything, just make sx go away and less likely to spread.
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Antifungals (4)
- Ketoconazole (imidazole) - Nizoral
- Triazole
- Terbafine - Lamisil
- Nystatin - Nystat RX
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Triazole (3)
- Fluconazole - Diflucan
- Itraconazole - Sporanox
- voriconazole - VFEND
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MOA antifungals
Interfere with proper product of cell membrane
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Antifungal counseling points
- Generally takes a long time to work (weeks). Except fluconazole on yeast infections.
- Side Effects: N/V/D
- Black Box: Azoles have lots of drug interactions with CYP450
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