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Transfusion reactions
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Cause of Acute HTR
Existing Ab vs RBC Ag
Mngment of Acute HTR
treat w/ vasopressors, IV fluid, and Corticosteroids
Prevention of acute HTR
Reduce Human Error
Nonhemolytic Febrile TR cause
Ab to donor leukocyte Ag
2° cause of NHFTR
accumulated cytokines in unit esp plts
preventions of NHFTR
Use Leukocyte reduced
treatment of NHFTR
Treat w/ an antipyretic (tylenol NOT asprin)
treatment of anaphlyactic reactions
pos pnt feet up, give flds, give epi, and give antihist, corticosteroids & B-2-agonists
Cause of anaphylactic
Ab to donor plasma prots (in pnts with congen IgA defic)
Preventing anaphylacytic
use IgA defic plasma, use washed cells
Cause of TRALI
Donor WBC Ab that react with host leukocytes
Prevention of Trali
None; exclude Multi pregnancy F from donations
Treatment of Trali
Provide respiratory support
Cause of Urticarial Reactions
Ab to donor plasma prots
Treatment for urticarial reactions
Antihistomines and slow or temp stop xfusion.
Preventions for urticarial
Administer antihistomines before xfusion.
Author
chikiko
ID
64073
Card Set
Transfusion reactions
Description
Transfusion reactions
Updated
2011-02-04T11:38:26Z
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