Physiology 6

  1. Aerobic metabolism
    in the mitochondria, fatty acids such as pyruvic acid and use of amino acids. Need oxygen
  2. anaerobic metabolism
    in the cytoplasm which is glucose to pyruvic acid, use of creatine. takes place in the cytoplasm when no oxygen is present.
  3. glyconeogenolysis
    is the breakdown of glycogen.
  4. creatine
    for use when no oxygen is avaiable. creatine phosphate+ ADP = ATP and phosphate. (you can buy creatine powder stupid though) Creatine kinease makes it a fast reaction, stored in the muscle cells.
  5. resting muscle metabolism
    fatty acids and o2 go into mitochondria (ATP and Creatine ADP cycle) Extra glucose from blood goes into glycogen stores.
  6. Moderate activity in muscle metabolism
    fatty acid and o2 go into mitochondria. Glucose from the blood when available if not then use glycogine stores turn into pyruvic acid (2 ATPs from that) and then that goes into mitcocondria and becomes 34 ATP
  7. Peak activity metabolism in the muscle
    glycogen to pyruvic but then no oxygen so it goes to lactic acid that exits the blood stream (creates 2 ATP) (Creatine and ADP still going on)
  8. Cori cycle
    2 lactate into 2 pyruvate to a new glucose (in the liver takes 6 ATP to do that though) then goes to muscle breaks down glucose to pyruvate for 2 ATP (takes 6 to make 2 not good bussiness but when times are rough), then pyruvate into lactic acid.
  9. Rigor mortis
    a fixed muscular contraction after death. (indicators of death) It takes a ATP to take myosin heads to release the myosin heads from the actin. Calcium builds up in the sarcoplasma lysosomes start to digest the protiens and then they get limber. (15-30 hrs get limber after 72)
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Physiology 6
Physiology lecture 6 moffat