Presynaptic terminal: fingerlike projections that are transmitting elements
soma: where neurotransmitters are produced
Where is K+ concentration the greatest?
in the cell
Where is Na+ concentration the greatest?
out of the cell
What is the permeability of a membrane (in terms of high or low for potassium or sodium)?
high for potassium
low for sodium
What is K+ equilibrium potential?
-120 mV
What is Na+ equilibrium potential?
+35 mV
What is depolarization?
lose - charge
What is repolarization?
Try to get back to -70
What is hyperpolarization?
increase - charge
What is threshold?
-55 mV
What does the Na/K pump do?
reestablish the concentration
Na OUT of cell
K IN cell
What is quantal release?
each synapse releases a set quantity of neurotransmitters
How is a neurotransmitter released?
Presynaptic neuron releases a neurotransmitter into the synaptic cleft and the neurotransmitter diffuses from 1 side to another then binds to post synaptic neuron.
What is myasthenia gravis?
receptors for Ach blocked at neurotransmitter junction so the muscles don't contract
What is a cause of depression?
decreased serotonin produced in the brain
Where is Acetylcholine produced?
neuromuscular junction
basal ganglia
parasympatheric post-ganglionic neurons
Where is dopamine produced?
substantia nigra
Where is norepinephrine produced?
brain stem
sympathetic post-ganglionic cells
Where is serotonin produced?
brainstem
Where is glycine produced?
spinal cord- inhibitory
Where is GABA (gamma aminobutyric acid) produced:
spinal cord- inhibitory
Where is Glutamate produced?
widespread- inhibitory
What is one ion that can cause an inhibitory post-synaptic potential
K+: causes hyperpolarization
What is one ion that can cause an excitatory post-synaptic potential?
Na+- causes depolarization
What is temporal summation?
combined effect of series of small potential changes causes depolarizations
frequency of action potentials
What is spatial summation?
receptors or synaptic potentials in different regions added together to cause depolarization
number of fibers processing action potentials
TRUE OR FALSE: EPSP-IPSP cancellation can NOT occur.
FALSE.
What are two things that can make an action potential occur faster?
axon diamter (more can get through at once)
myelination (prevents leakage)
What is saltatory conduction?
when an action potential proceedes down the myelinated axon jumping from node to node