-Helicases unwind and unzip the DNA by breaking hydrogen bonds
-creates a replication fork
Replication Initiation
DNA Polymerase adds complimentary nucleotides to each of the original strands
DNA Elongation
-DNA polymerase leaves
-Result: two separate and identical DNA molecules that are semi-conservative
DNA Termination
Semi-conservative means
in each double helix one strand is original and one is new
Shape of RNA
single stranded
In RNA, Thymine is changed to what nitrogenous base?
Uracil
A ribosome attaches to the mRNA and starts to code for the nitrogenous bases
Transcription Initiation
tRNA brings the corresponding amino acid to each codon as the ribosome moves down the mRNA strand.
Transcription Elongation
Reading of the final mRNA codon (aka the STOP codon), which ends the sythesis of the peptide chain and releases it.
Transcription Termination
DNA ----> mRNA
Transcription
mRNA ----> Protein
Translation
-ribosome attaches at start codon
-tRNA brings in methionine
translation initiation
-tRNA brings in amino acids to build polypeptide chain
translation elongation
-when stop codon is reached, ribosome detaches and polypeptide chain leaves
translation termination
a change in any single nucleotide of a DNA sequence
point mutation
the loss of one or more nucleotides in a DNA sequence
Deletions
the addition of one or more extra nucleotides in a DNA sequence
Insertions
Deletions and Insertions are categorized as ______ mutations
frameshift
three possible results from a point mutation, deletion, or insertion occuring:
Silent, Missense, Nonsense mutations
the mutation does not result in a change in the amino acid sequence
Silent mutation
a mutation that causes one amino acid in the protein sequence to be changed to a different one
Missense mutation
A mutation that results in a stop codon where there used to be a codon for an amino acid. This results in translation being stopped before the primary structure of the protein is complete