Lecture 9: Blood

Anisocytosis

abnormal RBC size
microcyte
macrocyte
- <6um
- >9um
Hereditary spherocytosis

defects in ankyrin, spectrin, or band 3.
Hereditary elliptocytosis

defects in spectrin or band 4.1
neutrophil
- PMN
- Primary, non-specific granules- azurophilic lysosome
- Secondary, specific granules- antimicrobial function
- Tertiary granules- phosphatases & metalloproteinases such as gelatinases/collagenases
- Band cells
- Integrin
Eosinophil
- stain red
- LARGER parasites- degranulate surpface of parasite
- major basic protein
basophils
- allergic
- release histamine-bronchial constriction & SMC vasodialation, serotonin
*anaphylatic shock- hypotension

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Lecture 9: Blood

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blood

Updated

2011-01-28T17:20:07Z

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