Lecture 10: Epithelium & Juntions

External lamina

for non-epithelial cells
Basolateral Junction:
- tight junction- sep apical from basolateral region
- lateral specialization- inflodings, inc SA
tight junction
- sep outside from inside.
- claudins (i.e. paracellular pathway) and occludins
zonula adherens

actin fil of terminal web insert into protein of zonula adherens by cadherins
desmosmes
- spot welds
- cadherins
- skin epithelium has preven abrasion
Hemidesmosomes

basal ends (basal lamina) connected through integrin

epidermolysis bullosa- hemidesmosome problem, blistering
Focal adhesion
- cell migation, (dis)assembly leading and lagging ends
- integrin links actin to fibronectin (ECM glycoprotein)
Gap Junctions
- intercellular communication
- identical connexin rings-> donut called connexOn, makes like a pathway

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Lecture 10: Epithelium & Juntions

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Epithelium & Juntions

Updated

2011-01-28T12:28:54Z

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