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Immunology
- Study of the immune system
- Biological basis for protection against infection
- Mediated by cells and proteins
- Latin term, immunis, meaning exempt
- Edward Jenner
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Vaccination
Deliberate induction of an immune response to a pathogen by introducing a dead or non-pathogenic form of the pathogen.
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Attenuated
Non-pathogenic
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Innate immunology
- From birth
- Relatively non-specific
- Fast, early part of response
- No memory
- Granulocytes
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Adaptive immunology
- Changes over time
- Specific
- Develops slowly
- Memory
- Lymphocytes
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Macrophage
 - Phagocytosis
- Antigen presentation
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Dendritic cell
- Antigen uptake
- Antigen presentation
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Neutrophil
- Phagocytosis
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Eosinophil
- Parasites
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Basophil
- ????????
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Mast Cell
Allergic Response
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Natural Killer cell
Virus killer
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Innate cells
- Macrophage
- Dendritic cell
- Neutrophil
- Eosinophil
- Basophil
- Mast Cell
- NK cell
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Adaptive Cells
- Lymphocytes
- B-cells
- T-cells
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B-cell
- originate and mature in bone marrow
- secrete antibody
- CD19+
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T-cell
- Originate in bone marrow and mature in Thymus
- Become effector T cells
- CD4+ - cell surface protein, kills bacteria
- CD8+ - viral and tumor
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