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3 Primary Bacterial Pathogenesis Factos:
- Host Susceptibility
- Bacterial Infectivity
- Virulence Factors
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What alters host susceptibility?
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What alters bacterial infectivity?
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What alters virulence factors?
- Pili
- Non-fimbrial adhesions
- Capsule
- Toxins
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Mannheimia haemolytica affects ____, but not ____
cattle, not dogs
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E. coli affects ____, but not ___
neonatal calves, but not adult cattle
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Specific strains of E. coli produce ___, causing _____ dz
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____ has a capsule to avoid phagocytosis
Pastruella multocida
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Pathogenic E. coli have pili to...
attach to mucosa and produce enterotoxin
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Pathogen-
organism that causes dz
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Infection-
establishment of pathogen in host
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Obligate Pathogen-
non oppertunistic
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ex. obligate pathogen:
Bacillus anthracis
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ex. Primary Pathogen and it's secondary pathogen
- Chlamydophila felis (conjunctiva in cats)
- Staphylococcus
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ex. Opportunistic Pathogen (2)
- E. coli -> UTI or otitis externa
- Staphylococcus w/ chlamydophilia felis in cats (also secondary pathogen)
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ex. of exogenous pathogen
Bacillus anthracis (soil-> animal)
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ex. of endogenous pathogen
Gingivitis in dogs from commensal
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ex. of contagious dz's (2)
- strangles in horses (streptococcus equi)
- Pneumonic Plague in cats and humans (yersinia pestis)
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Bordetella bronchiseptica enters via..
inhalation (dog -> cat -> pneumonia)
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Salmonella enters via...
ingestion (feed -> cattle)
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Lepto enters via...
Skin Abrasion, mucosa (water-> GI)
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Brucellosis canis enters via...
Urogenital tract
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Brucellosis enters via...
Placenta to fetus
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E. Coli in claves enters via...
umbilicus
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Horizontal transmission-
spread by contact, food, water
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Vertical transmission-
Transmission from mother to offsrping during pregnancy
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streptococcus equi is ___ specific
species
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Brucella abortus is ___ specific
organ
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