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Plasma membrane
- � Phospholipids bilayer; integral proteins; peripheral proteins,
- cholesterol; glycolipids; glycoproteins
- � Encloses cell contents; facilitates contact between other cells; provides receptors and mediates the entrance and exit of material into and out of the cell
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Cytoplasm
- � Cellular region between the plasma membrane and nucleus; consists of cytosol, dissolved solutes, organelles, and inclusions
- � Provides a medium in which chemical reactions occur
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Nucleus
- � Spherical/oval organelle ; surrounded by a nuclear membrane; contains nucleolus, nucleolus, and chromatin; may have one or more nucleoli
- � Direct cell activates and contains heredity material
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Ribosomes
- � Composed of ribosomal RNA and protein; 2 subunits of unequal size; not membrane bound; free or attached to the RER.
- � Protein synthesis
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Endoplasmic reticulum
- � Membranous network of tubular, double membrane channels; may or may not have ribosomes attached.
- � Aids in mechanical support of the cell; storage etc.
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Golgi apparatus
- � Stacks of flattened membranous sacs with explained vesicles near or at their ends
- o Packages secreted proteins and lipids
- o Responsible for carbohydrate syntheses and assembles glyco proteins
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Mitochondria
- � Double membranous bound spherical or rod-like structure; smooth outer membrane with folded inner membrane
- � Energy producer (ATP)
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Lysosomes
- � Membrane bound spheres; contains digestive enzymes
- � Digests foreign materials and microbes
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Peroxisomes
- � Small membrane bound spheres. Contains catalase.
- � Breaks down hydrogen peroxide into water and oxygen.
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Microfilaments
- � Small thread-like structures; not membrane bound; part of the cytoskeleton; Actin & myosin.
- � Provides shape and support; assists in cell movement; forms myofilaments in muscle tissues
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Microtubule
� Straight; slender cylinders; not membrane bound; part of
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cytoskeleton; tubulin
- � Supports and shape to cell
- � Helps in cellular conduction; forms flagella
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Centrioles
- � Paired cylindrical structures, each composed of nine triplets of microtubules; not membrane bound; located in the centrosome
- � Helps in cellular division
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Flagella
- � Long cytoplasm projection containing microtubules
- � Moves entire cell
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Cilia
- � Short cytoplasm projections containing microtubules. Covered by cell membrane
- � Moves substances along the cell
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Microvilli
- � Small finger like projections of the cell membrane on the free surface of the cell. Has a core of microfilaments
- � Increase surface area of contact between 2 cells
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Inclusions
- � Various chemical substances contained in the cell. usually produced by the cell Melanin, glycogen and lipids
- o Glycogen
- ? Provides energy or food reserve
- o Melanin
- ? Protects from UV light
- o Lipids
- ? Provide energy and good; protects organs, insulation
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Tissue
= aggregate of similarly specialized cells along with the extracellular material united to perform a particular function
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Connective tissue functions are:
Covering and lining the epithelium and glandular epithelium
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Basement membrane
An amorphous material secreted partly by epithelia cells and connective cells that lie adjacent to each other
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Epithelium definition
Tissue composed of closely packed cells with little to no intercellular substance
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What are the two types of epithelium?
�Glandular� & �Covering & lining�
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Cells are tightly packed and held together by
Junctonal complexes
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General functions of epithelial tissues?
Protection, absorption, secretion, excretion
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Simple
One layer of cells
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Stratified
Two or more layers of cells
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Pseudostratified (looks like)
All cells touch the BL but only some cells reach the free surface
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Squamous(looks like)
Flat
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Cuboidal (looks like)
As tall as it is wide
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Columnar (looks like)
Taller then it is wide
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Transitional (looks like)
Shape changes as organ stretches or releases
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Simple squamous epithelium e.g.
Boumans capsule (kidney), Alveoli (Lung), endothelium (blood vessels)
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Function of simple squamous epithelium
Filtration, diffusion secretion
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Simple cuboidal epithelium e.g.
Renal tubules, ducts of small glands�
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Function of simple cuboidal epithelium
Secretion & absorption
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Pseudostratified columnar epithelium with cilia (looks like)
All the cells touch the BL but they do not all reach the free surface; cells at the free surface are taller then wide an they have cilia
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Stratified squamous epithelium (looks like)
Many layers of cells; cells at the free surface are flat
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Stratified squamous epithelium e.g.
Epidermis of skin (keratinized (cells at free surface lack a nucleus), lines mouth, esophagus (nonkeratinized (cells at FS with nuclei).
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Function of stratified squamous epithelium
Protection
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Stratified cuboidal epithelium (looks like)
Many layers of cells; cells are the free surface are as tall as they are wide
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Stratified cuboidal epithelium.
Usually 2 rows, ducts of sweat glands
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Stratified cuboidal epithelium function
Lining
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Stratified columnar epithelium looks like
Many layers of cells; cells at the free surface are taller then wide
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Stratified transitional epithelium looks like
Many layers of cells; cells are the free surface change their shape (when organism is relaxed, cells at the free surface have a dome shape.
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Glandular epithelium
Cells are specialized for secretion; cells are closely packed and appear to be similar in structure; a free surface is difficult to see
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Mesenchyme
Embryonic tissue; lost of star shaped cells scattered thought out the matrix
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Lose (areolar) connective tissue
Lots of cells (fibroblasts, mast cells..)Randomly arranged within the matrix
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White adipose tissue
Lots of ball shaped cells; not much matrix visible
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Reticular connective tissue
Network of highly branching think fibers in a gel like substance; cells (reticular cells) cannot be seen with the special stain; fibbers often stain black
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Dense regular connective tissue
Abundance of collagen fibers arranged in parallel; few cells are arranged in rows between fibers; ground substance is hard to see
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Elastic connective tissue
Abundance of elastic fibers usually arranged in parallel; fibers usually stain black with a special stain; few cells and collagen fibers are present; ground substance is hard to see
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Dense irregular connective tissue
Abundance of collagen fivers arranged in many directions few cells are scattered thought out the matrix; ground substance is hard to see
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Hyaline cartilage
Cells occupy lacunae; abundance of ground substance; collage fivers are present but not readily visible
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Elastic cartilage
Cells occupy lacunae; abundance of ground substance; collagen fibers present but not readily visible; elastic fibers are present
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Fibrocartilage
Cells occupy lacunae; abundance of ground substance; bundles of collagenfivers arranged in herring bond patern; fibers visible; cells in rows between the fiber bundles
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Compact bone
Cells occupy lacunae; abundance of calcified matrix; distinct arrangement of components in compact bone
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Blood
Cells with nuclei (white) and witout nuclei (red and platelets) suspended in fluic matrix
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