PCOL_2

Mu Opiod Receptor AGONIST

• Mu Opiod Receptor AGONIST
• Active Metabolite: Morphine

• Mu Opiod Receptor AGONIST
• Demerol
• Active Metabolite: Normeperidine

• Mu Opiod Receptor AGONIST
• w/APAP = Vicodin
• w/Homatropine = Hycodan

• Mu Opiod Receptor AGONIST
• Ultram

• Mu Opiod Receptor AGONIST
• Nucynta

• Mu Opiod Receptor AGONIST
• controlled release = Oxycontin
• w/APAP = Percocet
• w/ASA = Percodan

Mu Opiod Receptor AGONIST

• Mu Opiod Receptor AGONIST
• Dilaudid

Mu Opiod Receptor AGONIST

Mu Opiod Receptor AGONIST

• Mu Opiod Receptor AGONIST
• Duragesic
• Actiq

• Mu Opiod Receptor AGONIST (periphery)
• w/Atropine = Lomotil

Mu Opiod Receptor AGONIST (periphery)

Mu Opiod Receptor AGONIST (periphery)

• Mu Opiod Receptor AGONIST (periphery)
• Deordorized tincture of opium

• Mu Opiod Receptor ANTAGONIST
• Narcan

• Mu Opiod Receptor ANTAGONIST
• ReVia (Oral)
• Vivitrol (IM)

Kappa AGONIST/ Mu ANTAGONIST

Kappa AGONIST/ Mu ANTAGONIST

• Kappa AGONIST/ Mu ANTAGONIST
• Talwin

• Kappa AGONIST/ Mu ANTAGONIST
• Talwin NX

• Mu PARTIAL AGONIST/ Kappa ANTAGONIST
• Subutex (Sublingual)

• Mu PARTIAL AGONIST/ Kappa ANTAGONIST
• Suboxone (Sublingual; Film tab)

• Benzodiazepine
• Versed
• Short-acting (3-8hours)

• Benzodiazepine
• Halcion
• Short-acting (3-8hrs)

• Benzodiazepine
• Xanax
• **Active Metabolites**
• Intermediate-acting (11-20hrs)

• Benzodiazepine
• Prosom
• Intermediate-acting (11-20hrs)

• Benzodiazepine
• Ativan
• Intermediate-acting (11-20hrs)

• Benzodiazepine
• Serax
• Intermediate-acting (11-20hrs)

• Benzodiazepine
• Restoril
• Intermediate-acting (11-20hrs)

• Benzodiazepine
• Librium
• **Active Metabolites**
• Long-acting ( >24hrs )

• Benzodiazepine
• Klonopin
• Long-acting ( >24hrs )

• Benzodiazepine
• Tranxene
• **Active Metabolites**
• Long-acting ( >24hrs )

• Benzodiazepine
• Valium
• **Active Metabolites**
• Long-acting ( >24hrs )

• Benzodiazepine
• Dlamane
• **Active Metabolites**
• Long-acting ( >24hrs )

• Benzodiazepine
• Doral
• **Active Metabolites**
• Long-acting ( >24hrs )

• Benzodiazepine-like
• Ambien

• Benzodiazepine-like
• Sonata

• Benzodiazepine-like
• Lunesta

• Benzodiazepine Antagonist
• Romazicon

• Barbiturates
• Pentothal
• Ultra-short acting (5-15mins)

• Barbiturates
• Brevital
• Ultra-short acting (5-15mins)

• Barbiturates
• Nembutal
• Ultra-short acting (5-15mins)

• Barbiturates
• Amytal
• Short-acting (3-8hrs)

• Barbiturates
• Butisol
• Short-acting (3-8hrs)

• Barbiturates
• Fioricet, Fiorinal
• Short-acting (3-8hrs)

• Barbiturates
• Mebaral
• Short-acting (3-8hrs)

• Barbiturates
• Seconal
• Short-acting (3-8hrs)

• Barbiturates
• Luminal
• Long-acting ( >24hrs )

• MT1 and MT2 Agonist
• Rozerem

• Partial Agonist at the 5HT-1A receptor
• Buspar

• Centrally-Acting Muscle Relaxant: Selective GABA_B AGONIST
• Lioresal

• Centrally-Acting Muscle Relaxant: Alpha₂ Receptor AGONIST
• Zanaflex

• Centrally-Acting Muscle Relaxant: 5-HT₂ Receptor ANTAGONIST
• works at spinal level
• Flexeril

• Centrally-Acting Muscle Relaxant
• works at spinal level
• Robaxin

• Centrally-Acting Muscle Relaxant
• works at spinal level
• Soma

• Centrally-Acting Muscle Relaxant
• works at spinal level
• Norflex

• Anti-Epileptic: Na⁺ Channel Blocker
• Dilantin or Phenytek

• Anti-Epileptic: Na+ Channel Blocker
• Cerebyx

• Anti-Epileptic: Na+ Channel Blocker
• Tegretol

• Anti-Epileptic: Na+ Channel Blocker
• Trileptal

• Anti-Epileptic: Na+ Channel Blocker
• Lamictal

• Anti-Epileptic: Na+ Channel Blocker & T-Type Ca⁺² Blocker
• Zonegran

• Anti-Epileptic: T-Type Ca⁺² Blocker
• Zarontin

• Anti-Epileptic: N-Type Ca⁺² Blocker
• Neurontin

• Anti-Epileptic: N-Type Ca⁺² Blocker
• Lyrica

Anti-Epileptic: main effects on GABA system to increase its inhibitory action

• Anti-Epileptic: main effects on GABA system to increase its inhibitory action
• Gabitril

• Anti-Epileptic: main effects on GABA system to increase its inhibitory action
• Sabril

• Anti-Epileptic: Na⁺ Blocer, T-Type Ca⁺² Blocker, and action to increase GABA system activity
• Depakote, Depakene, Sodium Valproate

• Anti-Epileptic:N-Type Ca⁺² Blocker, action to increase GABA system activity
• Keppra

• Anti-Epileptic: Na+ Blocer, N-Type Ca+2 Blocker, and AMPA Receptor Antagonist
• Topamax

• Anti-Epileptic: NMDA Receptor Antagonist
• Felbatol

Anti-Epileptic: action to increase GABA system activity, Non-competative Antagonist at the AMPA receptor

Inhalation Anesthetic

Inhalation Anesthetic

Inhalation Anesthetic

Inhalation Anesthetic

Inhalation Anesthetic

Inhalation Anesthetic

Intravenous Anesthetic

• Intravenous Anesthetic
• MOA: Voltage gated Na⁺ channel blocker; and GABA_A agonist

• Intravenous Anesthetic
• MOA: Agonist at GABA_A receptor

• Intravenous Anesthetic
• MOA: NMDA receptor antagonist; alpa₁ & beta₁ receptor agonist; and prevents reuptake of catecholamines

• Direct Acting Muscle Relaxant
• MOA: inhibits release of Ca⁺² release from sarcoplasmic reticulum via binding the ryanodine receptor
• Dantrium;Revonto

• Abortive Migraine TX
• Aspirin + Butalbital + Caffeine

• Abortive Migraine TX
• Acetominophen + Butalbital + Caffeiene

Abortive Migraine TX

• Abortive Migraine TX
• Treximet

• Abortive Migraine TX
• Imitrex

• Abortive Migraine TX
• Axert

• Abortive Migraine TX
• Zomig

• Abortive Migraine TX
• Amerge

• Abortive Migraine TX
• Maxalt

• Abortive Migraine TX
• Frova

• Abortive Migraine TX
• Relpax

• Abortive Migraine TX
• Ergot

• Abortive Migraine TX
• Ergot

• Abortive Migraine TX
• Ergot
• Methergine

• Abortive Migraine TX
• Ergot
• Cycloset;Parlodel

• Abortive Migraine TX
• NOT generally 1st line therapy, but think butorphanol...

• Preventitive Migraine TX
• Non-selective Beta Blocker
• Inderal

• Preventitive Migraine TX
• Ca⁺² Blocker
• Calan;Verelan

• Preventitive Migraine TX
• Increase GABA potentiation; inhibits Glutamate/NMDA receptors
• Depakote

• Preventitive Migraine TX
• Topamax

Preventitive Migraine TX

Preventitive Migraine TX

• Preventitive Migraine TX
• Botluinum Toxin Type A (Botox)

Ergot...bc who doesn't love tripping??

• Indirect-Acting Sympathomimetics: Amphetamines
• Adderall

• Indirect-Acting Sympathomimetics: Amphetamines
• Dexedrine

• Indirect-Acting Sympathomimetics: Amphetamines
• Desoxyn

• Indirect-Acting Sympathomimetics: Amphetamines
• Vyvanse

• Indirect-Acting Sympathomimetics: Methylphenidates
• Ritalin

• Indirect-Acting Sympathomimetics: Methylphenidates
• Concerta

• Indirect-Acting Sympathomimetics: Methylphenidates
• Focalin

• Misc. Indirect Acting Sympathomimetics
• Didrex

Misc. Indirect Acting Sympathomimetics

• Misc. Indirect Acting Sympathomimetics
• Brontil

• Misc. Indirect Acting Sympathomimetics
• Fenfluramine (or dexfenfluramine) + phentermine

• Misc. Indirect Acting Sympathomimetics
• Meridia

• Misc. Indirect Acting Sympathomimetics
• Provigil

• Misc. Indirect Acting Sympathomimetics
• Nuvigil

Misc. Indirect Acting Sympathomimetics

• Misc. Indirect Acting Sympathomimetics
• Strattera

• SNRI
• Effexor

• SNRI
• Pristiq

• SNRI
• Cymbalta

• SNRI
• Savella

• SSRI
• Luvox

• SSRI
• Zoloft

• SSRI
• Celexa

• SSRI
• Paxil

• SSRI
• Lexapro

• SSRI
• Prozac

• TCA
• Tofranil

• TCA
• Norpramin

• TCA
• Anafranil

• TCA
• Elavil

• TCA
• Pamelor

• TCA
• Silenor

• TCA
• Vivactil

• TCA
• Surmontil

TCA

TCA

• MAOI
• Nardil

• MAOI
• Parnate

• Atypical Antidepressant
• Wellbutrin

• Atypical Antidepressant
• Remeron

• Atypical Antidepressant
• Serzone

• Atypical Antidepressant
• Desyrel; Oleptro

• Used to treat mania in bipolar disorder
• inhibits NE release from adrenergic neurons and may also inhibit DA; Inhibits the PIP2 pathway so less 2nd messenger
• Eskalith; Lithobid

• Traditional Antipsychotics
• Thorazine

• Traditional Antipsychotics
• Mellaril

• Traditional Antipsychotics
• Prolixin

• Traditional Antipsychotics
• Trilafon

• Traditional Antipsychotics
• Stelazine

• Traditional Antipsychotics
• Navane

• Traditional Antipsychotics
• Haldol

• Traditional Antipsychotics
• Moban

• Traditional Antipsychotics
• Loxitane

• Traditional Antipsychotics
• Orap

• Atypical Antipsychotics
• Abilify

• Atypical Antipsychotics
• Clozaril

• Atypical Antipsychotics
• Zyprexa

• Atypical Antipsychotics
• Seroquel

• Atypical Antipsychotics
• Risperdal

• Atypical Antipsychotics
• Geodon

• Atypical Antipsychotics
• Invega

• Atypical Antipsychotics
• Latuda

• Atypical Antipsychotics
• Symbyax

AAAD Inhibitor

• AAAD Inhibitor
• Sinemet

• COMT Inhibitor
• Tasmar

• COMT Inhibitor
• Comtan

• COMT Inhibitor + AAAD Inhibitor
• Stalevo

• Dopamine Receptor Agonist: Ergot Derivative to TX Parkinson's
• Parlodel;Cycloset

Dopamine Receptor Agonist: Ergot Derivative to TX Parkinson's

• Dopamine Receptor Agonist: Ergot Derivative to TX Parkinson's
• Dostinex

• Dopamine Receptor Agonist
• Requip

• Dopamine Receptor Agonist
• Mirapex

• Dopamine Receptor Agonist
• Apokyn

• MAO-B Inhibitor
• TX Parkinson's
• Eldepryl

• MAO-B Inhibitor
• TX Parkinson's
• Azilect

• Muscarinic Receptor Antagonist
• TX Parkinson's
• Artane

• Muscarinic Receptor Antagonist
• TX Parkinson's
• Cogentin

• Cholinesterase Inhibitor
• Cognex

• Cholinesterase Inhibitor
• Aricept

• Cholinesterase Inhibitor
• Exelon

• Cholinesterase Inhibitor
• Razadyne

• Glutamate Receptor Antagonists
• Namenda

• Glutamate Receptor Antagonists
• Rilutek

• Mineralocorticoid Receptor Agonist
• Florinef

Glucocorticoid Receptor Agonist

Glucocorticoid Receptor Agonist

Glucocorticoid Receptor Agonist

Glucocorticoid Receptor Agonist

Glucocorticoid Receptor Agonist

Glucocorticoid Receptor Agonist

Glucocorticoid Receptor Agonist

Glucocorticoid Receptor Agonist

Acthrel

• ACTH
• Cortrosyn

Cortisol Synthesis Inhibitor

Cortisol Synthesis Inhibitor

Cortisol Synthesis Inhibitor

• Cortisol Synthesis Inhibitor
• ***high doses***