DNA repair

What is mutated in HNPCC
- MSH2
- MLH1
What sequences are mutated that identify parent strands?

GATC
What results from faulty mismatch repair?

HNPCC
What are the steps in base-excision repair?
- removal of base by a specific N-glycosylase
- removal of sugar and phosphate by AP-endonuclease and deoxyribose phosphate lyase
- DNA polymerase
- DNA ligase
Xeroderma pigmentosa results from a mutation in what gene?

XPA-XPG
Which 2 proteins control the entry of cell from G1 to S phase?

Rb and p53
Microsatellite instability often leads to what condition?

HNPCC

Author

pszurnicki

61384

Card Set

DNA repair

Description

DNA repair

Updated

2011-01-23T04:25:42Z

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