DNA replication

What acts as helicase in E.coli

DnaA then DnaB and then DnaC
What is a primosome?

Primase + prepriming complex
replication of which strand is discontinous and moving away from the replication fork?

Lagging strand
Which DNA pol in prokaryotes excises the primer and fills it in with nt?

DNA pol I
Which DNA pol elongates the primer?

DNA pol III
What is the only DNA pol that has repair exonuclease?

DNA pol I
What is the difference between topoisomerase one and two?
- One nicks one strand..no ATP
- Two nicks 2 strands..ATP involved
Whats another name for DNA topoisomerase two?

DNA gyrase
Novobiocin

Blocks binding of ATP to gyrase
Nalidixic acid and ciproflaxin

Block DNA gyrase
Camptothecin

Blocks human topo I..cancer drug
Etoposide, Etoposide

Blocks topo II..cancer drug
Which Prokaryotic DNA pol has 5' to 3' repair exonuclease

DNA pol I
Whats the only prokaryotic DNA pol that has 5' to 3' repair exonuclease

DNA pol I
proliferating cell nuclear antigen is analogous to what prokaryotic dna pol subunit

beta subunit---clamps dna to pol
what eukaryotic DNA pol elongates the growing chain?

Delta
what eukaryotic pol replicates mitochondial dna?

gamma
Polymerase alpha is what

Primase
what repetitive sequence do telemeres have

AGGGTT
DnaG is what in the prokaryotic replication?

Primase
Cyclophosphamide, Chlorambucil

Cross links DNA bases
What gene is mutated in HNPCC
- MSH2
- MLH

Author

pszurnicki

61380

Card Set

DNA replication

Description

DNA replication

Updated

2011-01-23T03:32:42Z

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