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the force of attraction of a molecule to a receptor site
affinity
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a drug that has a direct stimulatory effect on a receptor
agonist
-
a drug that interferes with the action of an agonist
antagonist
-
the dose above which no further beneficial drug effect will occur
ceiling dose
-
the administration of a drug through the gastrointestinal tract, by mouth
enteral
-
the magnitude of response obtained from optimal receptor site occupancy by a drug
efficacy
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the time it takes for half the drug to be removed from the body
half-life
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the ability to cause an effect or action
intrinsic activity
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the administration of a drug bypassing the GI tract, usually throug injection into the body in various ways but also including inhalation and topical administration
paranteral
-
a drug with affinity for the receptor site, but unable to produce a strong effect or action
partial agonist
-
the mechanisms of drug action involving biochemical and physiologic effects of drugs
pharmacodynamics
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the absorption, distribution, metabolism, and excretion of a drug
pharmacokinetics
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the use of pharmacologic agents to diagnose, treat, or prevent disease
pharmacotherapeutics
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the concentration at which the drug elicits 50% of its maximal response, related to the drug's affinity for the receptor
potency
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a specialized area on a cell or within a cell where a drug acts to initiate a series of biochemical and physiologic effects
receptor site
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drug that produces a significant physiologic response when only a relatively small number of receptors are occupied
strong agonist
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overdose, undesirable effects, or poisoning
toxicity
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