Reversibly blocks the action of cyclooxygenase which in turn prevents formation of prostaglandins. Causes analgesia equivalent to that of morphine sulfate
Indications
Acute moderate to severe pain
Contraindications
NSAID allergy, ASA sensitivity asthma, known peptic ulcer disease, recent GI bleed, renal failure, confirmed cerebrovascular bleeding, recent CABG, pregnancy
Precautions
Use cautiously with CHF and cirrhosis patients due to renal failure
Side Effects
GI bleeding
Inhibition of platelet aggregation
Acute renal failure
N/V
Diarrhea
Interactions
Potentiates medications that inhibit platelet aggregation
Dose and Route
Adult: 15-30 mg IV or 30-60 mg IM (single dose only)