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Whats a nucleotide???
part of a strand of DNA- phosphate, sugar, and nitrogen base
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what would be the complimentary DNA strand to ATGGCTTA?
TACCGAAT
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what is DNA?
deoxyribonucleic acid... genetic information; coding for everything our cells do- strands of phosphates, sugars, and nitrogen bases
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Whats chromatin?
present in interphase; spaghetti; DNA strands
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what are chromatids?
wound chromatin; two chromatids attached with a centromere make a chromosome; seperated in anaphase
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what are chromosomes?
two chromatids attached with a centromere; we have 46 chromosomes
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difference between mitosis and meiosis?
meiosis goes through mitosis twice; creates 4 daughter cells instead of 2; used to make gametes
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describe interphase!!!
nucleus intact, chromatin, 46 chromosomes!
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describe prophase!!!
DNA duplicates, nucleus dissolves, spindle fibres start to grow
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describe metaphase!!!
spindle fibres align chromosomes at the equator of the cell
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describe anaphase!!
spindle fibres pull chromosomes and pull chromatids to opposite poles of the cell
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describe telophase!!
- cytokinesis tingzzz (:
- cleavage furrowing, two daughter cells, nucleus reforms
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when does crossing over take place?
whats crossing over?
metaphase; synapsis- exchange of genetic information between chromosomes, allows genetic variation
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difference between haploid and diploid cells?
- haploid: n (gametes; 23)
- diploid: 2n (body cells; 46)
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what is oogenesis?
meiosis; production of ovum/eggs; gametes/haploid; only one viable egg
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what is spermatogenesis?
meiosis; production of sperm; gametes/haploid; all four sperm are viable
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define genotype!!
genetic make-up of an individual
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define phenotype!!!
visible alleles of an individual
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what is non-disjunction?
when sister chromatids don't seperate in anaphase
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what is trisomy 18?
non disjunction; causing a gamete to have one more chromosome 18; the zygote will have a third chromosome 18
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whats a monohybrid cross?
crossing ONE allele; punnett squares nd tingzz
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whats a dihybrid cross?
crossing TWO allels; punnett squares nd tingzz
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dominant vs. reccessive alleles
- dominant: will show even if only one of the two genes represents that allele
- recessive: needs both alleles to show; someone can be a carrier of a recessive gene
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homozygous vs. heterozygous
- homozygous: a pair of genes representing the same allele
- heterozygous: a pair of genes representing different genes
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what were Mendels laws?
- 1: law of segregation
- - only one version of an allele can be represented in a gamete
- 2: law of independent assortment
- - the inheritance of one trait doesn't affect the inheritance of another
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why did Mendel use pea plants in his experiment? (3 things)
- - they grow quickly
- - they can only show one trait or another
- - they are very low maintenance
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codominance vs. incomplete dominance?
- codominance: when the two versions of the allele are dominant and both alleles are present (i.e. red and white alleles would make a red and white striped individual)
- incomplete dominance: when the two versions of the allele are recessive and a blend of the alleles is shown (i.e. red and white would make a pink individual
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whats a test cross?
when the possibilities of an unknown genotype of an individual are crossed with a homozygous recessive individual to determine the unknown genotype
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why are males more affected with x-linked disorders?
because they only have one x-chromosome so they only need one affected chromosome to become affected
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advantages and disadvantages of asexual reproduction?
- advantages: faster, simpler, only requires one organism
- disadvantages: lack of genetic variation
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purpose of mitosis?
allows organisms to grow and repair
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whats cytokinesis?
the division of cytoplasm
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gamete vs. somatic cell?
- gamete: sex cell; haploid cell
- somatic cell: body cell; diploid cell
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where does spermatogenesis/oogenesis occur?
testes/ovaries
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when does spermatogensis/oogenesis occur?
puberty/embryo until birth
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length of mitotic production for spermatogenesis/oogenesis?
death/menopause
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what changes can occur in chromosome structure?
- deletion: a portion of the chromosome is lost
- duplication: a gene sequence is repeated
- inversion: a gene segments order is reversed
- translocation: a fragment of one chromosome attaches to another
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explain the cell cycle (the phases)
- S phase: synthesis; dna is replicated
- G1: gap between mitosis and S
- G2: gap between S and mitosis; cell is ready to divide
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what is cancer?
uncontrolled cell division
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how does someone get cancer?
carcinogens mutate the oncogenes which control the cell's replication mechanisms
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what is angiogenesis? (cancer)
the process of developing a system of arteries and veins to supply blood to the tumour
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what is metastasis? (cancer)
when some of the cancer cells break loose and move through the blood stream to another part of the body where it starts to multiply
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what are the two basic treatments for cancer?
surgery to remove the tumour (metasticized parts could be small) /radiation to kill the cancer cells (also kills other cells, some cells may be immune)
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eukaryotic vs. prokaryotic cells?
eukaryotic has a nucleus/ prokaryotic doesn't
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whats a karyotype?
an ordered display of an individual's chromosomes from mitotic cells; staining can reveal band patterns
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whats a homologous pair of chromosomes?
pairs of chromosomes with the same banding pattern; one from the mother one from the father (minus x and y)
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autosomal crosses, test crosses, sex-linked crosses, blood type crosses,
yeeeeeeeeeeeeeeeee!!! (:
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