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What is epidemiology?
Patterns of disease or health in a population
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Epi- Demo- Logy-
- Upon, people, study
- Study of what is upon the people
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Disease
Not fine or normal due to infection
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Two types of disease
- Infection- due to microbes
- Downs- other factors such as lifestyle
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Leading cause of death at the beginning of the 1900s
Lung infection (pneumonia)
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Leading causes of death in 2000
- Heart disease
- cancer
- stroke
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Obesity rate in Mexico
69.5%
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Top 4 countries in rates of obesity
- 1. Mexico
- 2. United States
- 3. New Zealand
- 4. UK
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Obesity rate in US
60-66%
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Factors that may cause early onset of puberty
- 1. Obesity
- 2. Hormones in Food
- 3. Chemicals in food packaging
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Describe two ways in which epidemiology may be considered a liberal arts discipline
- 1. Use of interdisciplinary approach
- 2. Use of the scientific method
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State three important landmarks in the history of epidemiology
- 1. Pandemic Influenza (Spanish Flu) 1918
- 2. The connection of cholera outbreaks with water sources by John Snow.
- 3. Eradication of smallpox.
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Analytic Epidemiology
A type of epidemiology that examines causal hypotheses regarding the association between exposures and health conditions.
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Descriptive epidemiology
Epidemiologic studies that are ocncerned with characterizing the amount and distribution of health and disease within a population.
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Determinant
A factor or event that is capable of bringing about a change in the health status of a population. i.e. microbe.
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Distribution
The occurrence of diseases and other health outcomes varies in populations, with some subgroups of the population more frequently affected than others.
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Epidemic
Occurrence of a disease clearly in excess of normal expectancy.
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Epidemiologic Transition
A shift in the pattern of moribidity and mortality from causes related primarily to infectious and communicable diseases to causes associated with chronic, degenerative disease.
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Epidemiology
Concerned with the distribution and determintants of health and disease, morbidity, injuries, disability, and mortality in populations.
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Exposure
Contact with a disease-causing factor; the amount of the factor that impinges upon a group or individuals.
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John Snow
An Enligish anestisiologist who innovated epidemiologic methods to identify the source of a cholera outbreak.
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Morbidity
Occurrence of an illness or illnesses in a population.
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Mortality
Occurrence of a death in a population.
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Natural Experiment
A type of research design in which the experimenter does not control the manipulation of a study factor. The manipulation of the study factor is a result of natural phenomena or policies that impact heath.
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Observational Science
A science that capitalizes on naturally occurring situations in order to study the occurrecne of disease.
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Outcome
A result that may arise form an exposure.
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Pandemic
An epidemic that spans a wide geographic area, and crosses international borders.
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Population
All the inhabitants of a given country or area considered together.
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3 types of prevention of disease
- Primary- Prevention of the disease before it occurs.
- Secondary- Activities that limit the progression of disease
- Tertiary- Restoring optimal functioning in a patient
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Risk
The probability that an event will occur; that an individual will become ill or die within a stated period of time or by a certain age.
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Risk assessment
Methodology to provide quantitative measurements of risks to health.
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Risk Factor
An exposure that is associated with a disease, morbidity, mortality, or adverse health outcome.
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Uses of Epidemiology
- Historical- Study the history and health of populations
- Community health- diagnose the health of the community
- Health Services- study the working of health services
- Risk assessment- Estimate individuals' risks of disease, accident or defect.
- Disease causality- Search for the causes of health and disease
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Hippocrates
- Greek authority departed from superstitous reasons for disease outbreak
- Wrote: On Airs, Waters, and Places
- Suggested disease might be associated with environmental factors
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Black Death
- 1346-1352
- Claimed 1/3 of the population of Europe (20-30 million)
- Caused by Y. pestis infection from flea bites
- Swollen lymph nodes, fever, necrosis of skin
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Paracelsus
- One of the founders of toxicology
- dose-response relationship
- notion of target organ specificity of chemicals
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Graunt
- published: 1. Natural and Political Observations Mentioned in a Following Index
- 2. Made Upon the Bills of Mortality
- First to employ quantitative methods
- Known as the Columbus of statistics
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Ramazzini
- Founder of the field of occupational medicine
- Authored De Morbis Artificum Diatriba (Disease of Workers)
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Pott
- First person to describe environmental cause of cancer
- Observed that chimney sweeps had a high incedence of scrotal cancer
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Jenner
Developed a method for smallpox vaccination in 1796
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Snow
Believed cholera was transmitted by contaminated water and was able to demonstrate this association
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Farr
- Developed a more sophisticated system for codifying medical conditions
- Examined possible link between mortality rates and population density
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Koch
Dmonstrated the association between a microorgansim and disease
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Langmuir
- First cheif epidemiologist for the CDC
- Established EIS
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Koch's Postulates
- 1.The organism must be observed in every case of the disease
- 2. It must be isolated and grown in pure culture
- 3. The pure culture must, when inoculated into a susceptible animal, reproduce the disease
- 4. The organism must be observed in, and recovered from, the experimental animal
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Alexander Fleming
- Discovered penicillin in 1928
- Penicillin is derived from the mold Penicillium notatum
- It was available by the end of WWII
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Demographic Transition
A shift from high birth and death rates in agrarian societies to much lower birth and death rates in developed countries.
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