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Endocrine 1

  1. D2 receptor antagonist
    • stimulates lactation
    • domperidone
  2. Recombinent DNA
    to treat dwarfism: inc GH

    • serostom
    • genotropin

    • for pit. dwarfism or GH def. short plasma t1/2 (20min)- longer biological (9-17hrs)
    • base on IGF-1 levels
  3. somatostatin analogs
    to treat inc GH

    • octreotide
    • lanreotide (long acting)
  4. Recombinent IGF-1
    use to increase IGF-1
  5. synthetic GHRH
    to increase GH

    sermorelin
  6. GH receptor antagonist
    for gigantism/ acromalegy

    pegvisomat

    dec IGF-1
  7. Dopamine agaonist
    • bromocriptine (parlodel)
    • cabergloine
    • pergolide

    • inc dopamine via D2 to dec GH
    • SE: n/v postural hopotension
Author
Anonymous
ID
6001
Card Set
Endocrine 1
Description
hypothalamus, calcium, androgens, estrogens, thyroid
Updated

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