-
ABC model
Model for the genetic basis of flower formation; products of three master genes (A, B, C) control the development of sepals, petals, and stamens and carpels from meristematic tissue.
-
acetylation
The attachment of an acetyl group (CH3CO) to an organic compound.
-
Barr body
Of the two X chromosomes in the somatic cells of female mammals, the one that has been condensed.
-
cell differentiation
In developing embryos of multicelled organisms, the process by which different cell lineages selectively express a different fraction of their genome and thereby become specialized in their composition, structure, and function.
-
dosage compensation
A gene control mechanism in female mammals in which most genes on one of two X chromosomes in somatic cells are inactivated; ensures that X chromosome genes are expressed at the same levels as in males (XY).
-
enhancers
A small sequence in DNA that binds transcription-regulating molecules; enhances transcription rates.
-
gene controls
A molecular mechanism that governs if, when, or how a specific gene is transcribed or translated.
-
homeotic genes
One of a class of master genes; helps determine identity of body parts during embryonic development.
-
hormones
[Gk. hormon, stir up] Signaling molecule secreted by one cell that can alter activities of any cell with receptors for it.
-
introns
One of the noncoding sequences in eukaryotic genes; it is excised from the pre-mRNA transcripts before translation.
-
knockout experiments
An experiment in which a living organism is engineered so that one of its genes does not function.
-
methylation
Attachment of a methyl group to an organic compound; also a common gene control mechanism.
-
mosaic tissue effect
In female mammals, an outcome of random X chromosome inactivation; different patches of tissue are expressing different X-linked alleles.
-
negative control
Control mechanism by which one or more regulatory proteins slow down a cell activity.
-
operator
Part of an operon; a DNA binding site for a regulatory protein.
-
operon
Group of bacterial genes together with a promoter�operator DNA sequence that controls their transcription.
-
pattern formation
In animal embryonic development, the sculpting of specialized tissues and organs from clumps of cells in the proper places, in the proper order by way of embryonic induction.
-
polytene chromosomes
Of some insects, a chromosome consisting of many parallel copies of the same DNA molecule.
-
positive control
Use of regulatory proteins to promote gene expression.
-
promoter
Short stretch of DNA to which RNA polymerase binds. Transcription then begins at the gene closest to the promoter.
-
promoters
Short stretch of DNA to which RNA polymerase binds. Transcription then begins at the gene closest to the promoter.
-
regulatory proteins
Part of mechanisms that control transcription, translation, and gene products by interacting with DNA, RNA, new polypeptide chains, or proteins such as enzymes.
-
repressor
Type of protein that can block transcription of a prokaryotic gene by binding to an operator.
-
selective gene expression
Outcome of controls over which gene products a cell makes or activates in a specified interval. Basis of cell differentiation.
-
X chromosome inactivation
In a female mammalian embryo, the programmed painting of special RNAs over most of one of the two X chromosomes, which cuts off access to the majority of its genes. Which X chromosome gets painted in each cell is a random event, so tissues of adult female mammals are a mosaic of traits. See also Dosage compensation.
|
|